Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27789989 | 0.82 | ALDH1A1 (0.34) | ALDH1A1HSD17B10GAAKDM4EHTT | |
| SCHEMBL5559414 | 0.81 | LMNA (0.40) | KMT2AALDH1A1HSD17B10GAAKDM4E | |
| SCHEMBL27790155 | 0.81 | DAO (0.35) | HSD17B10GAAKDM4EHTTTP53 | |
| SCHEMBL5553811 | 0.80 | MAPT (0.40) | KMT2AALDH1A1HSD17B10GAAKDM4E | |
| SCHEMBL5800049 | 0.79 | KMT2A (0.37) | KMT2AHSD17B10GAAKDM4EHTT | |
| SCHEMBL27768461 | 0.79 | KDM4E (0.31) | HSD17B10GAAKDM4EHTTTP53 | |
| SCHEMBL2006156 | 0.79 | AKR1C3 (0.45) | KMT2AKDM4EMAPTRAB9ATSHR | |
| SCHEMBL5558604 | 0.79 | SRC (0.47) | KMT2AALDH1A1HSD17B10KDM4ETSHR | |
| SCHEMBL15062606 | 0.78 | KDM4E (0.30) | HSD17B10GAAKDM4EHTTTP53 | |
| SCHEMBL5560588 | 0.78 | MAPT (0.39) | KMT2AALDH1A1HSD17B10GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050234030-A1 | Modulators of CRTH2, COX-2 and FAAH | IRONWOOD PHARMACEUTICALS, INC. | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234030-A1 | Modulators of CRTH2, COX-2 and FAAH | FAAH2, FAAH, PTGES2 | KMT2A 2147/4885ALDH1A1 970/4885HSD17B10 1119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.