Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.30 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6419655 | 0.83 | PTGDR2 (0.37) | PTGDR2CYP1A2CYP2C9CYP2C19PDK2 | |
| SCHEMBL6421750 | 0.81 | CHRM5 (0.43) | CHRM5CHRM1PTGDR2CYP1A2ALOX5 | |
| SCHEMBL6422824 | 0.79 | CHRM5 (0.41) | CHRM5CHRM1PTGDR2PDK2ALOX5 | |
| SCHEMBL6422956 | 0.78 | CHRM5 (0.42) | CHRM5CHRM1 | |
| SCHEMBL6420249 | 0.77 | PTGDR2 (0.36) | PTGDR2PDK2P2RX7NAMPT | |
| SCHEMBL6419465 | 0.77 | PDK2 (0.36) | CHRM5CHRM1PTGDR2CYP2C9PDK2 | |
| SCHEMBL6420518 | 0.76 | CHRM2 (0.36) | CHRM5CHRM1PDK2 | |
| SCHEMBL6419627 | 0.74 | HRH3 (0.35) | PTGDR2PDK2P2RX7 | |
| SCHEMBL6421015 | 0.74 | GRIN2B (0.38) | CYP1A2CYP2C9CYP2C19PDK2 | |
| SCHEMBL6420631 | 0.74 | PTGDR2 (0.34) | CHRM5CHRM1PTGDR2PDK2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908926-B1 | Substituted imidazoles, their preparation and use | NOVO NORDISK A/S (DK) | 2005-06-21 | — | — | US | disclosed |
| EP-1173438-A1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000063208-A1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-10-26 | — | — | WO | disclosed |