Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 6/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | MMP8 | P22894 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6422563 | 0.79 | PKM (0.53) | MMP13PKMMMP8HTTNPSR1 | |
| SCHEMBL4071220 | 0.79 | PKM (0.54) | MMP13PKMMMP8HTTNPSR1 | |
| SCHEMBL7937531 | 0.76 | ALDH1A1 (0.51) | MMP13PKMMMP8HTTNPSR1 | |
| SCHEMBL6708168 | 0.75 | PKM (0.64) | MMP13PKMMMP8HTTNPSR1 | |
| SCHEMBL3250372 | 0.75 | PKM (0.64) | MMP13PKMMMP8HTTNPSR1 | |
| SCHEMBL9705169 | 0.74 | PKM (0.61) | MMP13PKMMMP8HTTNPSR1 | |
| SCHEMBL14468640 | 0.72 | PKM (0.59) | MMP13PKMMMP8HTTNPSR1 | |
| SCHEMBL11797251 | 0.72 | PKM (0.59) | MMP13PKMMMP8HTTNPSR1 | |
| SCHEMBL9109608 | 0.72 | PKM (0.59) | MMP13PKMMMP8HTTNPSR1 | |
| SCHEMBL9703007 | 0.72 | HTT (0.66) | MMP13PKMMMP8HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929519-B1 | BETA-SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASES INHIBITORS | UPJOHN CO (US) | 2005-02-23 | — | — | EP | claimed |