Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.48 |
| ▸ | CNR1 | P21554 | 6/20 | 0.48 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 7/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6462625 | 0.87 | SIGMAR1 (0.52) | DRD2HTR2ACHRM1 | |
| SCHEMBL6458570 | 0.85 | POLB (0.49) | DRD2HTR2ACHRM1 | |
| SCHEMBL6457124 | 0.84 | ADRA1D (0.50) | DRD2HTR2ADRD3 | |
| SCHEMBL6466592 | 0.83 | HTR7 (0.55) | DRD2HTR2ADRD3 | |
| SCHEMBL6462987 | 0.83 | HTR7 (0.47) | — | |
| SCHEMBL6462598 | 0.82 | HTR7 (0.54) | DRD2HTR2ADRD3 | |
| SCHEMBL6465657 | 0.82 | HTR7 (0.57) | DRD2DRD3 | |
| SCHEMBL6458101 | 0.82 | HTR7 (0.54) | DRD2HTR2ADRD3 | |
| SCHEMBL6461236 | 0.82 | HTR7 (0.46) | CHRM1 | |
| SCHEMBL6470095 | 0.82 | EPHX2 (0.40) | DRD2HTR2AS1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1012147-B1 | O-SUBSTITUTED HYDROXYCUMARANONE DERIVATIVES AS ANTITUMOR AND ANTIMETASTATIC AGENTS | HOFFMANN LA ROCHE (CH) | 2005-11-02 | — | — | EP | disclosed |