Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6740807 | 0.87 | KMT2A (0.34) | KMT2AMAPTMEN1LMNATP53 | |
| SCHEMBL6734728 | 0.73 | KMT2A (0.34) | KMT2AMAPTMEN1LMNATP53 | |
| SCHEMBL6268444 | 0.73 | ADRA2B (0.37) | KMT2AMAPTMEN1GAABACE1 | |
| SCHEMBL6572332 | 0.71 | TDP1 (0.36) | KMT2AMAPTMEN1LMNATP53 | |
| SCHEMBL8521178 | 0.71 | ALDH1A1 (0.54) | KMT2AMAPTMEN1LMNATP53 | |
| SCHEMBL28087334 | 0.71 | ALDH1A1 (0.54) | KMT2AMAPTMEN1LMNATP53 | |
| SCHEMBL33874 | 0.71 | ALDH1A1 (0.54) | KMT2AMAPTMEN1LMNATP53 | |
| SCHEMBL6429126 | 0.70 | TDP1 (0.39) | KMT2AMAPTMEN1LMNATP53 | |
| SCHEMBL6572913 | 0.69 | KMT2A (0.38) | KMT2AMAPTMEN1LMNATP53 | |
| Hydrochloric Acid SCHEMBL7714474 | 0.69 | ALDH1A1 (0.52) | KMT2AMAPTMEN1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6951574-B2 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY (US) | 2005-10-04 | — | — | US | disclosed |
| US-6887280-B2 | Hair coloring compositions for use in oxidative hair dyeing | THE PROCTER & GAMBLE COMPANY (US) | 2005-05-03 | — | — | US | disclosed |
| US-6835213-B2 | Such as 3-(4-amino-3-hydroxy-phenyl)-propionitrile; for intense yellow color/improved colorfastness | THE PROCTER & GAMBLE COMPANY | 2004-12-28 | — | — | US | disclosed |
| US-20040255403-A1 | Primary intermediates for oxidative coloration of hair | LIM MU-ILL (US) | 2004-12-23 | — | — | US | disclosed |
| US-6765093-B2 | 4-(3-AMINO-2-HYDROXYPROPOXY)-M-PHENYLENEDIAMINE COUPLERS; 3-AMINO GROUP IS OPTIONALLY SUBSTITUTED | THE PROCTER & GAMBLE COMPANY | 2004-07-20 | — | — | US | disclosed |
| US-6750339-B2 | SUCH AS 4-AMINO-2-(2-DIMETHYLAMINO-ETHYL)-PHENOL; USEFUL IN PLACE OF P-AMINOPHENOL | THE PROCTER AND GAMBLE COMPANY | 2004-06-15 | — | — | US | disclosed |
| US-20020148052-A1 | Primary intermediates for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2002-10-17 | — | — | US | disclosed |
| US-20020144361-A1 | Novel couplers for use in oxidative hair dyeing | WELLA OPERATIONS US, LLC | 2002-10-10 | — | — | US | disclosed |
| US-20020138919-A1 | Novel couplers for use in oxidative hair dyeing | WELLA OPERATIONS US, LLC | 2002-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040255403-A1 | Primary intermediates for oxidative coloration of hair | COX5A, CYC1, MT-CO1 | KMT2A 1922/4885MAPT 3727/4885MEN1 3441/4885 |
| US-20020138919-A1 | Novel couplers for use in oxidative hair dyeing | CBR1, CBR3, MT-CO1 | KMT2A 1962/4885MAPT 3531/4885MEN1 3662/4885 |
| US-20020148052-A1 | Primary intermediates for oxidative coloration of hair | CYC1, MT-CO1, MT-ND1 | KMT2A 3360/4885MAPT 4587/4885MEN1 2579/4885 |
| US-20020144361-A1 | Novel couplers for use in oxidative hair dyeing | CBR1, CBR3, MT-CO1 | KMT2A 3161/4885MAPT 4697/4885MEN1 3832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.