Fluoride Ion

Fluoride Ion

SCHEMBL64308

C[P+](C)(C)Cc1ccccc1.[F-].[F-].[F-].[H+].[H+]

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.52
TAAR1 Q96RJ0 5/20 0.52
SLC6A2 P23975 3/20 0.52
SLC6A4 P31645 2/20 0.52
SLC6A3 Q01959 2/20 0.52
MAOA P21397 1/20 0.52
CYP2A6 P11509 1/20 0.52
ADORA2A P29274 1/20 0.52
ADORA1 P30542 1/20 0.52
SLC18A2 Q05940 1/20 0.48
CYP2D6 P10635 1/20 0.48
TRPA1 O75762 2/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
EPHX1 P07099 1/20 0.44
TP53 P04637 1/20 0.43
ADRA2B P18089 1/20 0.43
ADRA2C P18825 1/20 0.43
HTR2A P28223 1/20 0.43
ADRA1A P35348 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride Ion SCHEMBL28882550 0.97 SIGMAR1 (0.54) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
Fluoride Ion SCHEMBL4615583 0.97 SIGMAR1 (0.54) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
Hydrochloric Acid SCHEMBL516365 0.92 SIGMAR1 (0.54) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL9752209 0.92 SIGMAR1 (0.54) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
Water SCHEMBL2496495 0.92 SIGMAR1 (0.54) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
Bromide SCHEMBL515994 0.92 SIGMAR1 (0.54) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
Iodide SCHEMBL931546 0.92 SIGMAR1 (0.54) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL7176065 0.88 SIGMAR1 (0.46) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL7183353 0.88 SIGMAR1 (0.46) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL7181583 0.88 SIGMAR1 (0.46) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8207184-B2 Condensation compound between fluorinated cyclopentane ring and aromatic ring, and process for producing the same SUMITOMO CHEMICAL CO., LTD. (JP) 2012-06-26 US disclosed
US-8158275-B2 Fluorine-containing compound and method for producing same, fluorine-containing polymer, organic thin film, and organic thin film device OSAKA UNIVERSITY (JP) 2012-04-17 US disclosed
US-8129400-B2 Condensation compound between fluorinated cyclopentane ring and aromatic ring, and process for producing the same SUMITOMO CHEMICAL CO., LTD. (JP) 2012-03-06 US disclosed
US-20110282073-A1 CONDENSATION COMPOUND BETWEEN FLUORINATED CYCLOPENTANE RING AND AROMATIC RING, AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL CO., LTD. (JP) 2011-11-17 US disclosed
US-20110213162-A1 CONDENSATION COMPOUND BETWEEN FLUORINATED CYCLOPENTANE RING AND AROMATIC RING, AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL CO., LTD. (JP) 2011-09-01 US disclosed
US-8008336-B2 Forming electronic material, semiconductors SUMITOMO CHEMICAL CO., LTD. (JP) 2011-08-30 US disclosed
US-20100171102-A1 FLUORINE-CONTAINING POLYCYCLIC AROMATIC COMPOUND, FLUORINE-CONTAINING POLYMER, ORGANIC THIN FILM AND ORGANIC THIN FILM DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-07-08 US disclosed
EP-2133321-A1 FLUORINE-CONTAINING POLYCYCLIC AROMATIC COMPOUND, FLUORINE-CONTAINING POLYMER, ORGANIC THIN FILM AND ORGANIC THIN FILM DEVICE Sumitomo Chemical Company, Limited (JP) 2009-12-16 EP disclosed
US-20090240014-A1 FLUORINE-CONTAINING COMPOUND AND METHOD FOR PRODUCING SAME, FLUORINE-CONTAINING POLYMER, ORGANIC THIN FILM, AND ORGANIC THIN FILM DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-09-24 US disclosed
EP-1997821-A1 FLUORINE-CONTAINING COMPOUND AND METHOD FOR PRODUCING SAME, FLUORINE-CONTAINING POLYMER, ORGANIC THIN FILM, AND ORGANIC THIN FILM DEVICE Osaka University (JP) 2008-12-03 EP disclosed
US-20080207922-A1 Condensation Compound Between Fluorinated Cyclopentane Ring and Aromatic Ring, and Process for Producing the Same SUMITOMO CHEMICAL CO., LTD (JP) 2008-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080207922-A1 Condensation Compound Between Fluorinated Cyclopentane Ring and Aromatic Ring, and Process for Producing the Same RCC1, AFF4, TPR SIGMAR1 4003/4885TAAR1 1073/4885SLC6A2 3974/4885
US-20100171102-A1 FLUORINE-CONTAINING POLYCYCLIC AROMATIC COMPOUND, FLUORINE-CONTAINING POLYMER, ORGANIC THIN FILM AND ORGANIC THIN FILM DEVICE AFF1, RFT1, AFF2 SIGMAR1 527/4885TAAR1 117/4885SLC6A2 41/4885
US-20110213162-A1 CONDENSATION COMPOUND BETWEEN FLUORINATED CYCLOPENTANE RING AND AROMATIC RING, AND PROCESS FOR PRODUCING THE SAME RCC1, AFF4, TPR SIGMAR1 4003/4885TAAR1 1073/4885SLC6A2 3974/4885
US-20110282073-A1 CONDENSATION COMPOUND BETWEEN FLUORINATED CYCLOPENTANE RING AND AROMATIC RING, AND PROCESS FOR PRODUCING THE SAME RCC1, AFF4, TPR SIGMAR1 4003/4885TAAR1 1073/4885SLC6A2 3974/4885
US-20090240014-A1 FLUORINE-CONTAINING COMPOUND AND METHOD FOR PRODUCING SAME, FLUORINE-CONTAINING POLYMER, ORGANIC THIN FILM, AND ORGANIC THIN FILM DEVICE AFF1, AFF2, RFT1 SIGMAR1 1450/4885TAAR1 128/4885SLC6A2 434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.