Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 3/20 | 0.54 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752209 | 0.94 | SIGMAR1 (0.54) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| Iodide SCHEMBL931546 | 0.94 | SIGMAR1 (0.54) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| Fluoride Ion SCHEMBL28882550 | 0.94 | SIGMAR1 (0.54) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| Bromide SCHEMBL515994 | 0.94 | SIGMAR1 (0.54) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| Fluoride Ion SCHEMBL4615583 | 0.94 | SIGMAR1 (0.54) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| Water SCHEMBL2496495 | 0.94 | SIGMAR1 (0.54) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| Fluoride Ion SCHEMBL64308 | 0.92 | SIGMAR1 (0.52) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| Bromide SCHEMBL28038138 | 0.90 | SIGMAR1 (0.50) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2870339 | 0.87 | SIGMAR1 (0.48) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7175865 | 0.87 | SIGMAR1 (0.48) | SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 663 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250233207-A1 | ZINC BATTERY ELECTROLYTE ADDITIVE | Octet Scientific, Inc. | 2025-07-17 | — | — | US | claimed |
| EP-3901189-B1 | STABLE DISPERSANT AND APPLICATION THEREOF IN PREPARING COPOLYMER POLYOLS | WANHUA CHEMICAL GROUP CO LTD (CN) | 2025-06-25 | — | — | EP | claimed |
| EP-3904416-B1 | MACROMONOMERIC STABILIZER, PREPARATION METHOD THEREOF, AND METHOD FOR PREPARING POLYMERIC POLYOL | WANHUA CHEMICAL GROUP CO LTD (CN) | 2023-04-19 | — | — | EP | claimed |
| CN-111363133-B | Macromolecular monomer stabilizer, preparation method thereof and method for preparing copolymer polyol by using macromolecular monomer stabilizer | 万华化学集团股份有限公司 | 2022-09-20 | — | — | CN | claimed |
| EP-3904416-A1 | MACROMONOMERIC STABILIZER, PREPARATION METHOD THEREOF, AND METHOD FOR PREPARING POLYMERIC POLYOL | Wanhua Chemical Group Co., Ltd. (CN) | 2021-11-03 | — | — | EP | claimed |
| CN-109836538-B | Polymer polyol and method for producing the same | 万华化学集团股份有限公司 | 2021-07-23 | — | — | CN | claimed |
| CN-111349229-B | Stable dispersants and their use in the preparation of copolymer polyols | 万华化学集团股份有限公司 | 2021-06-29 | — | — | CN | claimed |
| CN-111363133-A | Macromolecular monomer stabilizer, preparation method thereof and method for preparing copolymer polyol by using macromolecular monomer stabilizer | 万华化学集团股份有限公司 | 2020-07-03 | — | — | CN | claimed |
| CN-111349229-A | Stable dispersants and their use in the preparation of copolymer polyols | 万华化学集团股份有限公司 | 2020-06-30 | — | — | CN | claimed |
| CN-109836538-A | Polymer polyatomic alcohol and preparation method thereof | 万华化学集团股份有限公司 | 2019-06-04 | — | — | CN | claimed |
| EP-0561033-A1 | Polymeric phoshonium salts providng enhanced chemiluminescence from 1,2-dioxetanes | LUMIGEN, INC. (US) | 1993-09-22 | — | — | EP | claimed |
| US-4013715-A | PROCESS FOR THE MANUFACTURE OF 2-HALO-ETHANE-PHOSPHONIC ACID DIHALIDES AND VINYL-PHOSPHONIC ACID DIHALIDES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-22 | — | — | US | claimed |
| JP-6211720-A | — | — | None | — | — | JP | disclosed |
| US-20260139136-A1 | THERMOPLASTIC POLYMER COMPOSITION AND METHOD FOR PRODUCING THE SAME | DAIKIN INDUSTRIES, LTD. (JP) | 2026-05-21 | — | — | US | disclosed |
| US-20260132270-A1 | FLUORORUBBER COMPOSITION AND MOLDED ARTICLE | DAIKIN INDUSTRIES, LTD. (JP) | 2026-05-14 | — | — | US | disclosed |
| EP-4733355-A1 | FLUORORUBBER COMPOSITION AND MOLDED ARTICLE | Daikin Industries, Ltd. (JP) | 2026-04-29 | — | — | EP | disclosed |
| US-3992370-A | 1,1-Dichloro-1a,1b-dihydrodibenzo(b,f)cycloprop(d)azepine-6(1H)-carboxaldehyde | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-11-16 | — | — | US | disclosed |
| US-3972923-A | FROM AN ACYL HALIDE AND A PHOSPHONIC ACID DERIVATIVE | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-08-03 | — | — | US | disclosed |
| US-3962324-A | Process for preparing halogenomethane-phosphonic acid dihalides | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-06-08 | — | — | US | disclosed |
| US-3953479-A | Diglycidyl esters of C21 -cycloaliphatic dicarboxylic acid | WESTVACO CORPORATION (US) | 1976-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260139136-A1 | THERMOPLASTIC POLYMER COMPOSITION AND METHOD FOR PRODUCING THE SAME | PFN1, RAD54L, FGB | SLC6A2 4859/4885SLC6A3 4829/4885SIGMAR1 4300/4885 |
| US-20260132270-A1 | FLUORORUBBER COMPOSITION AND MOLDED ARTICLE | FBP1, OGDH, ACACB | SLC6A2 4724/4885SLC6A3 4864/4885SIGMAR1 4471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.