Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10042462 | 0.87 | TDP1 (0.47) | TDP1GAAMEN1KMT2ACTSK | |
| SCHEMBL8264461 | 0.86 | TDP1 (0.46) | TDP1GAAMEN1KMT2AHTT | |
| SCHEMBL14586334 | 0.85 | ALDH1A1 (0.45) | TDP1GAAMEN1KMT2ACTSK | |
| SCHEMBL1784924 | 0.84 | CTSK (0.51) | TDP1GAAMEN1KMT2ACTSK | |
| SCHEMBL6290055 | 0.83 | GAA (0.47) | TDP1GAAMEN1KMT2AHTT | |
| SCHEMBL14176770 | 0.83 | TDP1 (0.41) | TDP1GAAMEN1KMT2ACTSK | |
| SCHEMBL5768805 | 0.83 | ALDH1A1 (0.50) | TDP1GAAMEN1KMT2AHTT | |
| SCHEMBL12258798 | 0.82 | TDP1 (0.48) | TDP1GAAMEN1KMT2ACTSK | |
| SCHEMBL14196596 | 0.82 | CA12 (0.40) | TDP1GAAMEN1KMT2ACTSK | |
| SCHEMBL16140278 | 0.81 | GAA (0.43) | TDP1GAAMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8729030-B2 | Peptides that bind to the erythropoietin receptor | AFFYMAX, INC. (US) | 2014-05-20 | — | — | US | disclosed |
| US-8642545-B2 | Erythropoietin mimetic peptide derivative and its pharmaceutical salts, the preparation and uses thereof | JIANGSU HANSOH PHARMACEUTICAL CO., LTD (CN) | 2014-02-04 | — | — | US | disclosed |
| US-8642545-B2 | Erythropoietin mimetic peptide derivative and its pharmaceutical salts, the preparation and uses thereof | JIANGSU HANSOH PHARMACEUTICAL CO., LTD (CN) | 2014-02-04 | — | — | US | disclosed |
| US-20130079283-A1 | Erythropoitein Receptor Peptide Formulations and Uses | AFFYMAX, INC. (US) | 2013-03-28 | — | — | US | disclosed |
| US-8324159-B2 | Erythropoietin receptor peptide formulations and uses | AFFYMAX, INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-8324159-B2 | Erythropoietin receptor peptide formulations and uses | AFFYMAX, INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-20120165275-A1 | Nitrogen-Based Linkers for Attaching Modifying Groups to Polypeptides and Other Macromolecules | AFFYMAX, INC. (US) | 2012-06-28 | — | — | US | disclosed |
| US-8106154-B2 | Nitrogen-based linkers for attaching modifying groups to polypeptides and other macromolecules | AFFYMAX, INC. (US) | 2012-01-31 | — | — | US | disclosed |
| US-8106154-B2 | Nitrogen-based linkers for attaching modifying groups to polypeptides and other macromolecules | AFFYMAX, INC. (US) | 2012-01-31 | — | — | US | disclosed |
| US-20110245176-A1 | NOVEL PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | AFFYMAX, INC. (US) | 2011-10-06 | — | — | US | disclosed |
| US-20090048166-A1 | NOVEL PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | AFFYMAX, INC. (US) | 2009-02-19 | — | — | US | disclosed |
| US-7414105-B2 | Peptide dimer bonded to polyethylene glycol through amide groups; insufficient or defective red blood cell production | AFFYMAX, INC. (US) | 2008-08-19 | — | — | US | disclosed |
| US-7414105-B2 | Peptide dimer bonded to polyethylene glycol through amide groups; insufficient or defective red blood cell production | AFFYMAX, INC. (US) | 2008-08-19 | — | — | US | disclosed |
| WO-2008095004-A2 | NITROGEN-BASED LINKERS FOR ATTACHING MODIFYING GROUPS TO POLYPEPTIDES AND OTHER MACROMOLECULES | AFFYMAX, INC. (US) | 2008-08-07 | — | — | WO | disclosed |
| US-20080090760-A2 | Compositions and Methods for Inhibiting Cellular Proliferation | HEMBROUGH TODD | 2008-04-17 | — | — | US | disclosed |
| US-20080081783-A1 | ERYTHROPOIETIN RECEPTOR PEPTIDE FORMULATIONS AND USES | AFFYMAX, INC. (US) | 2008-04-03 | — | — | US | disclosed |
| US-20070203066-A1 | Compositions and methods for inhibiting cellular proliferation | ENTREMED, INC. | 2007-08-30 | — | — | US | disclosed |
| US-20070104704-A1 | Erythropoietin receptor peptide formulations and uses | AFFYMAX, INC. (US) | 2007-05-10 | — | — | US | disclosed |
| US-20070104704-A1 | Erythropoietin receptor peptide formulations and uses | AFFYMAX, INC. (US) | 2007-05-10 | — | — | US | disclosed |
| US-20070032408-A1 | Novel spacer moiety for poly (ethylene glycol) modified peptide based compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165275-A1 | Nitrogen-Based Linkers for Attaching Modifying Groups to Polypeptides and Other Macromolecules | DNPEP, NGLY1, LNPEP | TDP1 2025/4885GAA 1083/4885MEN1 833/4885 |
| US-20090048166-A1 | NOVEL PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | EPOR, PROKR1, EDNRB | TDP1 4855/4885GAA 1929/4885MEN1 3831/4885 |
| US-20110245176-A1 | NOVEL PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | EPOR, PROKR1, EDNRB | TDP1 4855/4885GAA 1929/4885MEN1 3831/4885 |
| US-20130079283-A1 | Erythropoitein Receptor Peptide Formulations and Uses | EPOR, MPL, PROKR1 | TDP1 4849/4885GAA 2413/4885MEN1 1252/4885 |
| US-20080090760-A2 | Compositions and Methods for Inhibiting Cellular Proliferation | MKI67, VEGFA, HDGF | TDP1 4402/4885GAA 1565/4885MEN1 1098/4885 |
| US-20080081783-A1 | ERYTHROPOIETIN RECEPTOR PEPTIDE FORMULATIONS AND USES | EPOR, PROKR1, PROKR2 | TDP1 4804/4885GAA 1752/4885MEN1 2467/4885 |
| US-20070032408-A1 | Novel spacer moiety for poly (ethylene glycol) modified peptide based compounds | NGLY1, YWHAZ, PAM | TDP1 4727/4885GAA 1363/4885MEN1 1190/4885 |
| US-20070104704-A1 | Erythropoietin receptor peptide formulations and uses | EPOR, PROKR1, PROKR2 | TDP1 4804/4885GAA 1752/4885MEN1 2467/4885 |
| US-20070203066-A1 | Compositions and methods for inhibiting cellular proliferation | MKI67, VEGFA, HDGF | TDP1 4402/4885GAA 1565/4885MEN1 1098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.