SCHEMBL6433651

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6433871	0.87	MAPK8 (0.38)	CCNT1PTGESPTPRCMEN1KMT2A
	SCHEMBL7403971	0.85	AGTR1 (0.39)	MEN1KMT2AAGTR1NPC1PLG
	SCHEMBL6434389	0.80	PTPRC (0.49)	CCNT1PTPRCMEN1KMT2ADGAT2
	SCHEMBL7860463	0.76	KDM4E (0.49)	PTPRCMEN1KMT2AAGTR1ADRA1A
	SCHEMBL6436909	0.74	DGAT2 (0.50)	PTPRCMEN1KMT2ADGAT2ALDH1A1
	SCHEMBL7371013	0.73	AGTR1 (0.32)	CCNT1PTGESPTPRCMEN1KMT2A
	SCHEMBL6433655	0.73	ALDH1A1 (0.40)	MEN1KMT2APLAUALDH1A1MAPT
	SCHEMBL6433264	0.72	ROCK2 (0.44)	GAA
	SCHEMBL7397677	0.72	PLK1 (0.35)	MEN1KMT2AAGTR1MAPK8ADRA1A
	SCHEMBL6436403	0.72	PLAU (0.52)	NPC1PLGPLAUALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.