Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435103 | 0.83 | HTT (0.33) | HTT | |
| SCHEMBL6439454 | 0.73 | GAA (0.45) | HTT | |
| SCHEMBL6431994 | 0.72 | GAA (0.46) | HTT | |
| SCHEMBL6432336 | 0.70 | SMN1; SMN2 (0.37) | HTT | |
| SCHEMBL6435667 | 0.70 | MAPT (0.42) | HTT | |
| SCHEMBL6436802 | 0.69 | MAPT (0.44) | HTT | |
| SCHEMBL6414257 | 0.68 | GAA (0.39) | HTT | |
| SCHEMBL22213870 | 0.66 | CA12 (0.33) | — | |
| SCHEMBL24344820 | 0.65 | PAX8 (0.35) | — | |
| SCHEMBL24344233 | 0.63 | KCNQ3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044270-A1 | OXADIAZOLOPYRAZINE DERIVATIVES AS PHARMACEUTICALLY ACTIVE COMPOUNDS | 4SC AG (DE) | 2005-05-19 | — | — | WO | disclosed |