Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435528 | 0.83 | HTT (0.32) | HTT | |
| SCHEMBL6439454 | 0.76 | GAA (0.45) | HTTKMT2ALMNAHPGDPOLB | |
| SCHEMBL6431994 | 0.74 | GAA (0.46) | HTTKDM4EKMT2ALMNAALDH1A1 | |
| SCHEMBL6436341 | 0.73 | MAPK1 (0.42) | KDM4EKMT2AALDH1A1 | |
| SCHEMBL6435667 | 0.72 | MAPT (0.42) | HTTKMT2ALMNAALDH1A1POLB | |
| SCHEMBL6436802 | 0.71 | MAPT (0.44) | HTTKDM4EKMT2AALDH1A1HPGD | |
| SCHEMBL28281023 | 0.66 | TRPM8 (0.32) | — | |
| SCHEMBL2529611 | 0.62 | MT-CO2 (0.42) | KDM4E | |
| SCHEMBL31009098 | 0.62 | GPR119 (0.36) | LMNAALDH1A1POLB | |
| SCHEMBL27780944 | 0.62 | PKM (0.35) | HTTKMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044270-A1 | OXADIAZOLOPYRAZINE DERIVATIVES AS PHARMACEUTICALLY ACTIVE COMPOUNDS | 4SC AG (DE) | 2005-05-19 | — | — | WO | disclosed |