Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22472150 | 1.00 | TRPV1 (0.40) | TRPV1TRPA1ALDH1A1MAPTSPHK1 | |
| SCHEMBL21694380 | 1.00 | TRPV1 (0.40) | TRPV1TRPA1ALDH1A1MAPTSPHK1 | |
| SCHEMBL6434209 | 1.00 | TRPV1 (0.40) | TRPV1TRPA1ALDH1A1MAPTSPHK1 | |
| SCHEMBL7862202 | 1.00 | TRPV1 (0.40) | TRPV1TRPA1ALDH1A1MAPTSPHK1 | |
| SCHEMBL421671 | 1.00 | — | — | |
| SCHEMBL6440275 | 1.00 | TRPV1 (0.40) | TRPV1TRPA1ALDH1A1MAPTSPHK1 | |
| SCHEMBL21694371 | 1.00 | TRPV1 (0.40) | TRPV1TRPA1ALDH1A1MAPTSPHK1 | |
| SCHEMBL423131 | 0.97 | — | — | |
| SCHEMBL755558 | 0.88 | — | — | |
| SCHEMBL27904586 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240180932-A1 | SUBSTITUTED RESORCYLIC ACID COMPOUNDS IN THE MANAGEMENT OF AGEING AND RELATED DISORDERS | NESTLE SA (CH) | 2024-06-06 | — | — | US | claimed |
| EP-4313017-A1 | SUBSTITUTED RESORCYLIC ACID COMPOUNDS IN THE MANAGEMENT OF AGEING AND RELATED DISORDERS | Société des Produits Nestlé S.A. (CH) | 2024-02-07 | — | — | EP | claimed |
| US-20240010589-A1 | SUBSTITUTED RESORCINOL COMPOUNDS AS AMPK ACTIVATORS, COMPOSITIONS, METHODS AND USES THEREOF | NESTLE SA (CH) | 2024-01-11 | — | — | US | claimed |
| US-20230414638-A1 | SUBSTITUTED RESORCYLIC ACID COMPOUNDS AS AMPK ACTIVATOR AND USES THEREOF | NESTLE SA (CH) | 2023-12-28 | — | — | US | claimed |
| WO-2023213715-A1 | AMPK ACTIVATOR (CBDA) AND SGLT2 INHIBITOR FOR METABOLIC HEALTH | Société des Produits Nestlé S.A. (CH) | 2023-11-09 | — | — | WO | claimed |
| CN-116981452-A | Substituted resorcinol compounds for the management of aging and related disorders | 雀巢产品有限公司 | 2023-10-31 | — | — | CN | claimed |
| EP-4247359-A1 | SUBSTITUTED RESORCINOL COMPOUNDS AS AMPK ACTIVATORS, COMPOSITIONS, METHODS AND USES THEREOF | Société des Produits Nestlé S.A. (CH) | 2023-09-27 | — | — | EP | claimed |
| CN-116761791-A | Substituted resorcinol compounds as AMPK activators and uses thereof | 雀巢产品有限公司 | 2023-09-15 | — | — | CN | claimed |
| EP-4240342-A1 | SUBSTITUTED RESORCYLIC ACID COMPOUNDS AS AMPK ACTIVATOR AND USES THEREOF | Société des Produits Nestlé S.A. (CH) | 2023-09-13 | — | — | EP | claimed |
| CN-116744911-A | Substituted resorcinol compounds as AMPK activators, compositions, methods and uses thereof | 雀巢产品有限公司 | 2023-09-12 | — | — | CN | claimed |
| WO-2022106557-A1 | SUBSTITUTED RESORCINOL COMPOUNDS AS AMPK ACTIVATORS, COMPOSITIONS, METHODS AND USES THEREOF | Société des Produits Nestlé S.A. (CH) | 2022-05-27 | — | — | WO | claimed |
| WO-2022096423-A1 | SUBSTITUTED RESORCYLIC ACID COMPOUNDS AS AMPK ACTIVATOR AND USES THEREOF | Société des Produits Nestlé S.A. (CH) | 2022-05-12 | — | — | WO | claimed |
| CN-113423470-B | Cosmetic compounding agent, cosmetic, and method for producing same | 三吉油脂株式会社 | 2024-07-09 | — | — | CN | disclosed |
| US-20240180932-A1 | SUBSTITUTED RESORCYLIC ACID COMPOUNDS IN THE MANAGEMENT OF AGEING AND RELATED DISORDERS | NESTLE SA (CH) | 2024-06-06 | — | — | US | disclosed |
| EP-4313017-A1 | SUBSTITUTED RESORCYLIC ACID COMPOUNDS IN THE MANAGEMENT OF AGEING AND RELATED DISORDERS | Société des Produits Nestlé S.A. (CH) | 2024-02-07 | — | — | EP | disclosed |
| US-20240010589-A1 | SUBSTITUTED RESORCINOL COMPOUNDS AS AMPK ACTIVATORS, COMPOSITIONS, METHODS AND USES THEREOF | NESTLE SA (CH) | 2024-01-11 | — | — | US | disclosed |
| EP-1067122-A2 | Phenylpyrimidine derivatives, process for preparing the same, liquid crystal compositions containing said derivatives as active ingredient, and liquid crystal elements using such compositions | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-10 | — | — | EP | disclosed |
| US-5723610-A | Alcohol reactants for forming phenylpyrimidine derivatives and process for preparing said alcohols | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-03-03 | — | — | US | disclosed |
| US-5539115-A | FERROELECTRIC CRYSTALS FOR OPTICAL APPARATUS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0435632-A2 | Phenylpyrimidine derivatives, process for preparing the same, liquid crystal compositions containing said derivatives as active ingredient, and liquid crystal elements using such compositions | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-07-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230414638-A1 | SUBSTITUTED RESORCYLIC ACID COMPOUNDS AS AMPK ACTIVATOR AND USES THEREOF | PRKAG2, PRKAB2, PRKAG1 | TRPV1 2165/4885TRPA1 3022/4885ALDH1A1 284/4885 |
| US-20240010589-A1 | SUBSTITUTED RESORCINOL COMPOUNDS AS AMPK ACTIVATORS, COMPOSITIONS, METHODS AND USES THEREOF | PRKAG2, PRKAG1, PRKAB2 | TRPV1 3189/4885TRPA1 3941/4885ALDH1A1 1040/4885 |
| US-20240180932-A1 | SUBSTITUTED RESORCYLIC ACID COMPOUNDS IN THE MANAGEMENT OF AGEING AND RELATED DISORDERS | HSPA9, CS, SQSTM1 | TRPV1 2609/4885TRPA1 3318/4885ALDH1A1 1472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.