Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.75 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.65 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.65 |
| ▸ | ESR1 | P03372 | 3/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.57 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14174986 | 0.82 | LTA4H (0.63) | LTA4HCHRNB2CHRNA4ESR1ESR2 | |
| SCHEMBL12744959 | 0.82 | LTA4H (0.58) | LTA4HCHRNB2CHRNA4KCNH2KCNA3 | |
| SCHEMBL5108600 | 0.81 | LTA4H (0.57) | LTA4HCHRNB2CHRNA4ESR1ESR2 | |
| SCHEMBL6802602 | 0.81 | LTA4H (0.61) | LTA4HCHRNB2CHRNA4ESR1ESR2 | |
| SCHEMBL5113291 | 0.81 | LTA4H (0.61) | LTA4HCHRNB2CHRNA4ESR1ESR2 | |
| SCHEMBL7608283 | 0.80 | CHRNB2 (0.56) | LTA4HCHRNB2CHRNA4ESR1ESR2 | |
| SCHEMBL12409068 | 0.80 | CHRNB2 (0.56) | LTA4HCHRNB2CHRNA4ESR1ESR2 | |
| SCHEMBL9520979 | 0.79 | LTA4H (0.51) | LTA4HCHRNB2CHRNA4KCNH2KCNA3 | |
| SCHEMBL27010001 | 0.79 | LTA4H (0.51) | LTA4HCHRNB2CHRNA4KCNA3LMNA | |
| SCHEMBL6902137 | 0.79 | TSHR (0.55) | LTA4HCHRNB2CHRNA4ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594857-A2 | N-MONOACYLATED O-PHENYLENEDIAMINES AS ANTI-CANCER AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-11-16 | — | — | EP | claimed |
| WO-2004069133-A2 | N-MONOACYLATED O-PHENYLENEDIAMINES AS ANTI -CANCER AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-08-19 | — | — | WO | claimed |
| US-11696953-B2 | Poly(beta-amino esters) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-07-11 | — | — | US | disclosed |
| US-20210388196-A1 | GENE DELIVERY CARRIER | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-12-16 | — | — | US | disclosed |
| US-11041069-B2 | Gene delivery carrier | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-06-22 | — | — | US | disclosed |
| US-20200172663-A1 | POLYMER-LIPIDS AND COMPOSITIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2020-06-04 | — | — | US | disclosed |
| US-20190194444-A1 | GENE DELIVERY CARRIER | POLITECNICO DI MILANO (IT) | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194444-A1 | GENE DELIVERY CARRIER | PAICS, PBDC1, BCAT1 | LTA4H 1361/4885CHRNB2 4025/4885CHRNA4 4038/4885 |
| US-20200172663-A1 | POLYMER-LIPIDS AND COMPOSITIONS | PHOSPHO1, PEBP1, PBDC1 | LTA4H 784/4885CHRNB2 4354/4885CHRNA4 3519/4885 |
| US-11041069-B2 | Gene delivery carrier | PAICS, PBDC1, BCAT1 | LTA4H 1361/4885CHRNB2 4025/4885CHRNA4 4038/4885 |
| US-20210388196-A1 | GENE DELIVERY CARRIER | PAICS, PBDC1, BCAT1 | LTA4H 1361/4885CHRNB2 4025/4885CHRNA4 4038/4885 |
| US-11696953-B2 | Poly(beta-amino esters) and uses thereof | BCAT1, BCAT2, SNRPE | LTA4H 1407/4885CHRNB2 1304/4885CHRNA4 1263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.