Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1617647 | 0.84 | — | — | |
| Ammonia Solution, Strong SCHEMBL10938310 | 0.81 | — | — | |
| Ethylene Glycol SCHEMBL15227546 | 0.71 | TSHR (0.56) | TSHR | |
| Ethylene Glycol SCHEMBL3427076 | 0.68 | TSHR (0.50) | TSHR | |
| Ethylene Glycol SCHEMBL3863316 | 0.68 | TSHR (0.50) | TSHR | |
| Ethylene Glycol SCHEMBL27399593 | 0.68 | TSHR (0.50) | TSHR | |
| Ethylene Glycol SCHEMBL15227459 | 0.68 | TSHR (0.50) | TSHR | |
| Ethylene Glycol SCHEMBL42568 | 0.68 | — | — | |
| Ethylene Glycol SCHEMBL3493119 | 0.68 | TSHR (0.50) | TSHR | |
| Ethylene Glycol SCHEMBL15013924 | 0.68 | TSHR (0.50) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190352262-A1 | New Pleuromutilin Antibiotic Compounds, Compositions and Methods of Use and Synthesis | UNIV YALE (US) | 2019-11-21 | — | — | US | disclosed |
| WO-2018144717-A1 | NEW PLEUROMUTILIN ANTIBIOTIC COMPOUNDS, COMPOSITIONS AND METHODS OF USE AND SYNTHESIS | YALE UNIVERSITY (US) | 2018-08-09 | — | — | WO | disclosed |
| US-9828338-B2 | Carbamate derivatives of lactam based N-acylethanolamine acid amidase (NAAA) inhibitors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-11-28 | — | — | US | disclosed |
| US-20160068482-A1 | CARBAMATE DERIVATIVES OF LACTAM BASED N-ACYLETHANOLAMINE ACID AMIDASE (NAAA) INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-03-10 | — | — | US | disclosed |
| US-6867305-B2 | Synthesis of epothilones, intermediates thereto and analogues thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2005-03-15 | — | — | US | disclosed |
| US-20020058817-A1 | Synthesis of epothilones, intermediates thereto and analogues thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160068482-A1 | CARBAMATE DERIVATIVES OF LACTAM BASED N-ACYLETHANOLAMINE ACID AMIDASE (NAAA) INHIBITORS | NAAA, FAAH, FAAH2 | TSHR 4069/4885 |
| US-20020058817-A1 | Synthesis of epothilones, intermediates thereto and analogues thereof | DHPS, PPOX, THPO | TSHR 2965/4885 |
| US-20190352262-A1 | New Pleuromutilin Antibiotic Compounds, Compositions and Methods of Use and Synthesis | PLEC, MLN, MRPL21 | TSHR 2760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.