Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CES1 | P23141 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | FBP1 | P09467 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Nitrophenol SCHEMBL309332 | 0.91 | TDP1 (0.61) | ALDH1A1TDP1CES1CA1CA2 | |
| P-Nitrophenol SCHEMBL14125735 | 0.91 | TDP1 (0.61) | ALDH1A1TDP1CES1CA1CA2 | |
| P-Nitrophenol SCHEMBL27462973 | 0.91 | TDP1 (0.60) | ALDH1A1TDP1CES1CA1CA2 | |
| P-Nitrophenol SCHEMBL17289474 | 0.89 | TDP1 (0.59) | ALDH1A1TDP1CES1CA1CA2 | |
| P-Nitrophenol SCHEMBL15203620 | 0.89 | ALDH1A1 (0.64) | ALDH1A1TDP1CES1CA1CA2 | |
| P-Nitrophenol SCHEMBL11048842 | 0.89 | CES1 (0.58) | ALDH1A1TDP1CES1CA1CA2 | |
| P-Nitrophenol SCHEMBL29806213 | 0.89 | CES1 (0.58) | ALDH1A1TDP1CES1CA1CA2 | |
| P-Nitrophenol SCHEMBL1839 | 0.89 | CES1 (0.58) | ALDH1A1TDP1CES1CA1CA2 | |
| P-Nitrophenol SCHEMBL324522 | 0.87 | TSHR (0.61) | ALDH1A1TDP1CES1CA1CA2 | |
| P-Nitrophenol SCHEMBL692178 | 0.87 | MAPK1 (0.61) | ALDH1A1TDP1CES1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 369 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836089-A | Compound for cytosolic delivery and preparation method thereof | 哈工大郑州研究院 | 2023-10-03 | — | — | CN | claimed |
| CN-116162071-A | Lipid compound, composition containing lipid compound, preparation method and application of lipid compound | 尧唐(上海)生物科技有限公司 | 2023-05-26 | — | — | CN | claimed |
| CN-112830897-B | Ureido-containing benzimidazole derivative and preparation method and application thereof | 石家庄以岭药业股份有限公司 | 2022-09-09 | — | — | CN | claimed |
| CN-113527270-A | Medicine intermediate of PROTAC molecule of targeted monoacylglycerol lipase, preparation method and application | 河南大学 | 2021-10-22 | — | — | CN | claimed |
| CN-112830897-A | Ureido-containing benzimidazole derivative and preparation method and application thereof | 石家庄以岭药业股份有限公司 | 2021-05-25 | — | — | CN | claimed |
| CN-109134541-B | Long-chain biotin marker and preparation method and application thereof | 伯科生物医学科技（北京）有限公司 | 2020-10-27 | — | — | CN | claimed |
| EP-2570416-B1 | Antiviral bisfuran derivative as hiv protease inhibitor and intermediates thereof | GILEAD SCIENCES INC (US) | 2016-03-16 | — | — | EP | claimed |
| WO-2016029146-A1 | SPECIFIC INHIBITORS OF METHIONYL-TRNA SYNTHETASE | UNIVERSITY OF WASHINGTON (US) | 2016-02-25 | — | — | WO | claimed |
| EP-1999133-B1 | PROCESS FOR PREPARATION OF HIV PROTEASE INHIBITORS | GILEAD SCIENCES INC (US) | 2013-08-21 | — | — | EP | claimed |
| US-20130172295-A1 | PROCESS FOR PREPARATION OF HIV PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2013-07-04 | — | — | US | claimed |
| EP-2570416-A1 | Antiviral bisfuran derivative as hiv protease inhibitor and intermediates thereof | Gilead Sciences, Inc. (US) | 2013-03-20 | — | — | EP | claimed |
| US-8173623-B2 | Process for preparation of HIV protease inhibitors | GILEAD SCIENCES, INC. (US) | 2012-05-08 | — | — | US | claimed |
| US-20110065631-A1 | PROCESS FOR PREPARATION OF HIV PROTEASE INHIBITORS | GILEAD SCIENCES, INC (US) | 2011-03-17 | — | — | US | claimed |
| US-20080004242-A1 | Process for preparation of HIV protease inhibitors | GILEAD SCIENCES, INC. | 2008-01-03 | — | — | US | claimed |
| EP-3766510-B1 | CONJUGATES AND PRODRUGS FOR USE IN THE TREATMENT OF CANCER AND INFLAMMATORY DISEASES | CENTRE NAT RECH SCIENT (FR) | 2026-05-13 | — | — | EP | disclosed |
| US-20260124190-A1 | METHOD FOR TREATING A DISEASE OR CONDITION USING A PYRAZOLE COMPOUND OR FORMULATION THEREOF | RIGEL PHARMACEUTICALS, INC. (US) | 2026-05-07 | — | — | US | disclosed |
| US-20260116913-A1 | NEUROSTEROID COMPOUNDS AND METHODS FOR THEIR PREPARATION AND USE IN TREATING CENTRAL NERVOUS SYSTEM DISORDERS | TEXAS A & M UNIV SYS (US) | 2026-04-30 | — | — | US | disclosed |
| WO-1997046251-A1 | aPL IMMUNOREACTIVE PEPTIDES, CONJUGATES THEREOF AND METHODS OF TREATMENT FOR aPL ANTIBODY-MEDIATED PATHOLOGIES | LAJOLLA PHARMACEUTICAL COMPANY (US) | 1997-12-11 | — | — | WO | disclosed |
| WO-1997033576-A1 | CARBAMYL GUANIDINE AND AMIDINE PRODRUGS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-09-18 | — | — | WO | disclosed |
| US-5194588-A | Inhibitors of human leukocyte elastase, di-, tri- and tetra-peptides | ICI AMERICAS INC. (US) | 1993-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172295-A1 | PROCESS FOR PREPARATION OF HIV PROTEASE INHIBITORS | PRSS1, PREP, SERPINB1 | ALDH1A1 2742/4885TDP1 2702/4885CES1 510/4885 |
| US-20260116913-A1 | NEUROSTEROID COMPOUNDS AND METHODS FOR THEIR PREPARATION AND USE IN TREATING CENTRAL NERVOUS SYSTEM DISORDERS | CHRNA9, HSD3B2, HSD3B1 | ALDH1A1 1411/4885TDP1 1511/4885CES1 2257/4885 |
| US-20260124190-A1 | METHOD FOR TREATING A DISEASE OR CONDITION USING A PYRAZOLE COMPOUND OR FORMULATION THEREOF | IRAK2, IRAK3, IRAK1 | ALDH1A1 2354/4885TDP1 2066/4885CES1 3596/4885 |
| US-20110065631-A1 | PROCESS FOR PREPARATION OF HIV PROTEASE INHIBITORS | PREP, PRSS1, SERPINB1 | ALDH1A1 1261/4885TDP1 2426/4885CES1 349/4885 |
| US-20080004242-A1 | Process for preparation of HIV protease inhibitors | PRSS1, PREP, SERPINB1 | ALDH1A1 2742/4885TDP1 2702/4885CES1 510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.