Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Methyl Ester SCHEMBL1474630 | 0.91 | CYP2C19 (0.47) | CYP2C19ELANEMAPTKDM4EGAA | |
| Maleic Acid SCHEMBL1664727 | 0.90 | CYP2C19 (0.59) | CYP2C19ELANEMAPTKDM4EGAA | |
| SCHEMBL3165671 | 0.86 | CYP2C19 (0.52) | CYP2C19ELANEMAPTMAPK1KMT2A | |
| SCHEMBL7897292 | 0.85 | CYP2C19 (0.49) | CYP2C19ELANEMAPTKDM4EGAA | |
| SCHEMBL7897294 | 0.85 | CYP2C19 (0.49) | CYP2C19ELANEMAPTKDM4EGAA | |
| SCHEMBL28161325 | 0.85 | CYP2C19 (0.49) | CYP2C19ELANEMAPTKDM4EGAA | |
| Acrylic Acid SCHEMBL1591920 | 0.85 | CYP2C19 (0.58) | CYP2C19ELANEMAPTKDM4EGAA | |
| Acrylic Acid SCHEMBL20918477 | 0.85 | CYP2C19 (0.58) | CYP2C19ELANEMAPTKDM4EGAA | |
| Acrylic Acid SCHEMBL8168043 | 0.85 | CYP2C19 (0.58) | CYP2C19ELANEMAPTKDM4EGAA | |
| Acrylic Acid SCHEMBL27988742 | 0.85 | CYP2C19 (0.58) | CYP2C19ELANEMAPTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1579845-B1 | Cosmetic composition comprising a polyglycerolated silicone elastomer | L'ORÉAL (FR) | 2017-04-19 | — | — | EP | disclosed |
| US-9017704-B2 | Composition comprising a block polymer and a film-forming agent | L'OREAL (FR) | 2015-04-28 | — | — | US | disclosed |
| US-8992903-B2 | Composition comprising at least one block polymer and at least one gelling agent | L'OREAL (FR) | 2015-03-31 | — | — | US | disclosed |
| US-8728451-B2 | Styling composition comprising, in a predominantly aqueous medium, a pseudo-block polymer, processes employing same and uses thereof | L'OREAL (FR) | 2014-05-20 | — | — | US | disclosed |
| US-8119110-B2 | Film forming ethylene oxide-propylene oxide block polymer | L'OREAL S.A. (FR) | 2012-02-21 | — | — | US | disclosed |
| US-7932324-B2 | Block polymers and cosmetic compositions and processes comprising them | L'OREAL (FR) | 2011-04-26 | — | — | US | disclosed |
| US-7915347-B2 | Block polymers and cosmetic compositions and processes comprising them | L'OREAL S.A. (FR) | 2011-03-29 | — | — | US | disclosed |
| US-7875265-B2 | A cosmetic composition comprising a specific block polymer and a specific plasticizer intended to be applied to human keratinous substances, such as the skin, lips, eyelashes, eyebrows, nails or hair; film-forming acrylic polymers containing a plasticizer; flexibility; good hold; transfer-free | L'OREAL (FR) | 2011-01-25 | — | — | US | disclosed |
| US-7803877-B2 | Block polymers and cosmetic compositions and processes comprising them | L'OREAL S.A. (FR) | 2010-09-28 | — | — | US | disclosed |
| EP-1518534-B1 | Bilayered cosmetic product, uses thereof and kit-of-parts containing this product. | OREAL (FR) | 2010-07-14 | — | — | EP | disclosed |
| US-20060093568-A1 | Composition comprising a block polymer and a film-forming agent | L'OREAL S.A. (FR) | 2006-05-04 | — | — | US | disclosed |
| US-20050220723-A1 | Aerosol device comprising a propellant and a styling composition comprising, in a predominantly aqueous medium, a pseudo-block polymer and an additional fixing polymer; processes therefor and uses thereof | L'OREAL S.A. (FR) | 2005-10-06 | — | — | US | disclosed |
| US-20050220747-A1 | Styling composition comprising, in a predominantly aqueous medium, a pseudo-block polymer, processes employing same and uses thereof | L'OREAL S.A. (FR) | 2005-10-06 | — | — | US | disclosed |
| EP-1579845-A2 | Cosmetic composition comprising a polyglycerolated silicone elastomer | L'OREAL (FR) | 2005-09-28 | — | — | EP | disclosed |
| US-20050106197-A1 | Cosmetic composition comprising a block polymer and a non-volatile silicone oil | L'OREAL S.A. (FR) | 2005-05-19 | — | — | US | disclosed |
| US-20050095213-A1 | Two-coat cosmetic product, cosmetic process of using thereof and makeup kit containing this product | L'OREAL S.A. (FR) | 2005-05-05 | — | — | US | disclosed |
| WO-2005030155-A1 | CONTINUOUS AQUEOUS PHASE-BASED PHOTOPROTECTIVE COMPOSITION CONTAINING A POLYMER COMPRISING AT LEAST TWO BLOCKS INCOMPATIBLE WITH EACH OTHER AND HAVING DIFFERENT GLASS TRANSITION TEMPERATURES | L'ORÉAL (FR) | 2005-04-07 | — | — | WO | disclosed |
| WO-2005030158-A1 | COSMETIC COMPOSITION COMPRISING A TENSIONING AGENT AND A PARTICULAR BLOCK ETHYLENIC POLYMER | L'OREAL (FR) | 2005-04-07 | — | — | WO | disclosed |
| EP-1518534-A2 | Bilayered cosmetic product, uses thereof and kit-of-parts containing this product. | L'OREAL (FR) | 2005-03-30 | — | — | EP | disclosed |
| US-20040120920-A1 | Novel block polymers and cosmetic compositions and processes comprising them | L'OREAL S.A. (FR) | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060093568-A1 | Composition comprising a block polymer and a film-forming agent | KRT18, CUTA, DSG1 | CYP2C19 3609/4885ELANE 839/4885MAPT 499/4885 |
| US-20050220747-A1 | Styling composition comprising, in a predominantly aqueous medium, a pseudo-block polymer, processes employing same and uses thereof | POLR1C, NACA, PIK3C3 | CYP2C19 1084/4885ELANE 4322/4885MAPT 1574/4885 |
| US-20050095213-A1 | Two-coat cosmetic product, cosmetic process of using thereof and makeup kit containing this product | CUTA, PRKACB, PRKDC | CYP2C19 4071/4885ELANE 1106/4885MAPT 1381/4885 |
| US-20050220723-A1 | Aerosol device comprising a propellant and a styling composition comprising, in a predominantly aqueous medium, a pseudo-block polymer and an additional fixing polymer; processes therefor and uses thereof | POLR1C, SUCLG1, POLB | CYP2C19 3384/4885ELANE 4353/4885MAPT 1086/4885 |
| US-20040120920-A1 | Novel block polymers and cosmetic compositions and processes comprising them | FANCI, GDI2, TBCB | CYP2C19 2716/4885ELANE 3403/4885MAPT 1240/4885 |
| US-20050106197-A1 | Cosmetic composition comprising a block polymer and a non-volatile silicone oil | KRT18, CUTA, DSG1 | CYP2C19 3005/4885ELANE 532/4885MAPT 741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.