SCHEMBL3165671

SCHEMBL3165671

C=C(C=CC(=O)O)C(=O)OC1CC2CCC1(C)C2(C)C

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.52
ELANE P08246 2/20 0.47
MAPT P10636 1/20 0.47
MAPK1 P28482 1/20 0.47
KMT2A Q03164 1/20 0.47
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
CYP19A1 P11511 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid Methyl Ester SCHEMBL1474630 0.91 CYP2C19 (0.47) CYP2C19ELANEMAPTMAPK1KMT2A
SCHEMBL644739 0.86 CYP2C19 (0.50) CYP2C19ELANEMAPTMAPK1KMT2A
SCHEMBL1412655 0.84 MAPT (0.49) CYP2C19ELANEMAPTMAPK1KMT2A
SCHEMBL4162354 0.83 CYP2C19 (0.67) CYP2C19ELANEMAPTMAPK1KMT2A
SCHEMBL8106018 0.83 CYP2C19 (0.67) CYP2C19ELANEMAPTMAPK1KMT2A
SCHEMBL1617700 0.83 CYP2C19 (0.67) CYP2C19ELANEMAPTMAPK1KMT2A
SCHEMBL7958498 0.83 LMNA (0.46) CYP2C19ELANEMAPTMAPK1KMT2A
SCHEMBL29199857 0.83 MAPT (0.53) CYP2C19MAPTMAPK1KMT2AALDH1A1
Maleic Acid SCHEMBL1664727 0.83 CYP2C19 (0.59) CYP2C19ELANEMAPTMAPK1KMT2A
SCHEMBL3174990 0.83 CYP2C19 (0.48) CYP2C19ELANEMAPTMAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107405294-A Sunscreen composition and method 欧莱雅 2017-11-28 CN claimed
US-20100203004-A1 COSMETIC COMPOSITION CONTAINING A TENSIONING AGENT AND AN ACRYLIC POLYMER L'OREAL (FR) 2010-08-12 US disclosed
EP-2205197-A1 COSMETIC COMPOSITION CONTAINING A TENSIONING AGENT AND AN ACRYLIC POLYMER L'Oreal (FR) 2010-07-14 EP disclosed
US-20100009931-A1 ASSOCIATION OF A TENSOR AGENT OR DEVICE AND A SACCHARIDE COMPOUND L'OREAL (FR) 2010-01-14 US disclosed
US-20090285770-A1 Topical Compositions for Promoting Homeostasis of the Skin L'OREAL (FR) 2009-11-19 US disclosed
WO-2009056545-A1 COSMETIC COMPOSITION CONTAINING A TENSIONING AGENT AND AN ACRYLIC POLYMER L'OREAL (FR) 2009-05-07 WO disclosed
US-20080305069-A1 Cosmetic Use of Tensing Agents to Improve the Thickness of the Skin and/or the Radiance of the Complexion L'OREAL (FR) 2008-12-11 US disclosed
EP-1951191-A1 TOPICAL COMPOSITIONS FOR PROMOTING HOMEOSTASIS OF THE SKIN L'Oréal (FR) 2008-08-06 EP disclosed
EP-1951378-A1 COSMETIC USE OF TENSING AGENTS TO IMPROVE THE THICKNESS OF THE SKIN AND/OR THE RADIANCE OF THE COMPLEXION L'Oréal (FR) 2008-08-06 EP disclosed
US-20080181953-A1 COMPOSITION CONTAINING A TENSIONING POLYMER AND HYBRID PARTICLES, METHODS OF USE L'OREAL (FR) 2008-07-31 US disclosed
US-20070166269-A1 Cosmetic composition containing a statistical polymer with a linear chain of ethylenic nature L'OREAL (FR) 2007-07-19 US disclosed
WO-2007057452-A1 COSMETIC USE OF TENSING AGENTS TO IMPROVE THE HOMEOSTASIS OF THE SKIN AND/OR THE RADIANCE OF THE COMPLEXION L'ORÉAL (FR) 2007-05-24 WO disclosed
WO-2007057448-A1 TOPICAL COMPOSITIONS FOR PROMOTING HOMEOSTASIS OF THE SKIN L'ORÉAL (FR) 2007-05-24 WO disclosed
WO-2007057451-A1 COSMETIC USE OF TENSING AGENTS TO IMPROVE THE THICKNESS OF THE SKIN AND/OR THE RADIANCE OF THE COMPLEXION L'ORÉAL (FR) 2007-05-24 WO disclosed
WO-1999007014-A1 INTERPOSER/ADHESIVE COMPOSITE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-02-11 WO disclosed
EP-0723559-B1 ACRYLAMIDO FUNCTIONAL DISUBSTITUTED ACETYL ARYL KETONE PHOTOINITIATORS MINNESOTA MINING & MFG (US) 1997-07-09 EP disclosed
EP-0723559-A1 ACRYLAMIDO FUNCTIONAL DISUBSTITUTED ACETYL ARYL KETONE PHOTOINITIATORS MINNESOTA MINING & MFG (US) 1996-07-31 EP disclosed
US-5506279-A IRRADIATION, CROSSLINKABLE, POLYMERIZABLE PHOTOSENSITIZERS; PRESSURE SENSITIVE ADHESIVES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-04-09 US disclosed
WO-1995010552-A1 ACRYLAMIDO FUNCTIONAL DISUBSTITUTED ACETYL ARYL KETONE PHOTOINITIATORS LOWELL ENGINEERING CORPORATION (US) 1995-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070166269-A1 Cosmetic composition containing a statistical polymer with a linear chain of ethylenic nature POLH, LAGE3, ELOVL6 CYP2C19 1081/4885ELANE 45/4885MAPT 1068/4885
US-20080181953-A1 COMPOSITION CONTAINING A TENSIONING POLYMER AND HYBRID PARTICLES, METHODS OF USE CUTA, COL14A1, SOST CYP2C19 1641/4885ELANE 2180/4885MAPT 823/4885
US-20090285770-A1 Topical Compositions for Promoting Homeostasis of the Skin CUTA, PIEZO1, TSLP CYP2C19 4822/4885ELANE 987/4885MAPT 2792/4885
US-20100009931-A1 ASSOCIATION OF A TENSOR AGENT OR DEVICE AND A SACCHARIDE COMPOUND PIEZO1, TRPA1, TREH CYP2C19 4531/4885ELANE 2265/4885MAPT 2292/4885
US-20100203004-A1 COSMETIC COMPOSITION CONTAINING A TENSIONING AGENT AND AN ACRYLIC POLYMER PHOSPHO1, CUTA, SGMS1 CYP2C19 3801/4885ELANE 2490/4885MAPT 2920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.