Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | F9 | P00740 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | CTSG | P08311 | 1/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7112889 | 0.79 | CYP3A4 (0.53) | CNR1CNR2ALDH1A1CYP3A4NAAA | |
| SCHEMBL9472352 | 0.78 | LMNA (0.45) | CA12CA7CA9CA14F9 | |
| Hydrochloric Acid SCHEMBL11651001 | 0.76 | CNR1 (0.46) | CNR1CNR2ALDH1A1NAAAPOLB | |
| SCHEMBL11845564 | 0.76 | NAAA (0.43) | CNR1CNR2ALDH1A1SMN1; SMN2NAAA | |
| SCHEMBL28352839 | 0.76 | KMT2A (0.47) | CA12CA7CA9CA14ALDH1A1 | |
| SCHEMBL7330779 | 0.74 | CTSS (0.54) | — | |
| SCHEMBL7332020 | 0.74 | MME (0.54) | CNR1CNR2ALDH1A1HPGD | |
| SCHEMBL13846307 | 0.74 | CTSD (0.44) | CNR1CNR2ALDH1A1LMNACYP2C19 | |
| SCHEMBL11776768 | 0.74 | KMT2A (0.48) | ALDH1A1CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL7398925 | 0.74 | SLC15A1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101326151-B | Improved method for the production of ramipril | SANOFI AVENTIS DEUTSCHLAND | 2015-01-07 | — | — | CN | disclosed |
| US-8119375-B2 | Method for the production of ramipril | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20090017509-A1 | METHOD FOR THE PRODUCTION OF RAMIPRIL | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-01-15 | — | — | US | disclosed |
| CN-101326151-A | Improved method for the production of ramipril | SANOFI AVENTIS DEUTSCHLAND (DE) | 2008-12-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090017509-A1 | METHOD FOR THE PRODUCTION OF RAMIPRIL | REN, PDE8B, PDE3A | CA12 4086/4885CA7 2086/4885CA9 2793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.