Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6450384 | 1.00 | MLYCD (0.43) | MLYCDALDH1A1NPC1RAB9AGAA | |
| SCHEMBL7062432 | 0.84 | HCAR2 (0.47) | ALDH1A1NPC1RAB9AL3MBTL1KMT2A | |
| SCHEMBL7062429 | 0.84 | HCAR2 (0.47) | ALDH1A1NPC1RAB9AL3MBTL1KMT2A | |
| SCHEMBL6462011 | 0.83 | MAOB (0.41) | ALDH1A1CYP1A1CYP1B1MAOBPTGDR2 | |
| SCHEMBL6462008 | 0.83 | MAOB (0.41) | ALDH1A1CYP1A1CYP1B1MAOBPTGDR2 | |
| SCHEMBL19511062 | 0.81 | LMNA (0.43) | MLYCDALDH1A1KMT2ACES2ACHE | |
| SCHEMBL2003283 | 0.80 | MAPT (0.48) | MLYCDALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL2003282 | 0.80 | MAPT (0.48) | MLYCDALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL6454587 | 0.76 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9AGAAL3MBTL1 | |
| SCHEMBL15248923 | 0.76 | CA12 (0.65) | L3MBTL1KMT2AMAOBMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6852751-B2 | Difluorobutyric acid metalloprotease inhibitors | THE PROCTER & GAMBLE COMPANY (US) | 2005-02-08 | — | — | US | disclosed |
| US-20030139453-A1 | Difluorobutyric acid metalloprotease inhibitors | THE PROCTER & GAMBLE COMPANY | 2003-07-24 | — | — | US | disclosed |
| EP-1265865-A2 | DIFLUOROBUTYRIC ACID DERIVATIVES AND THEIR USE AS METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001070693-A2 | DIFLUOROBUTYRIC ACID DERIVATIVES AND THEIR USE AS METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2001-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139453-A1 | Difluorobutyric acid metalloprotease inhibitors | DPEP1, TMPRSS15, FAP | MLYCD 1861/4885ALDH1A1 251/4885NPC1 1376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.