Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.59 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | JUN | P05412 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9967696 | 1.00 | CYP11B1 (0.59) | CYP11B1CYP11B2ALOX5CHRNB2CHRNA4 | |
| SCHEMBL10193817 | 0.85 | ALOX5 (0.55) | CYP11B1CYP11B2ALOX5CHRNB2CHRNA4 | |
| SCHEMBL3012381 | 0.83 | CYP11B1 (0.53) | CYP11B1CYP11B2ALOX5CHRNB2CHRNA4 | |
| SCHEMBL3012379 | 0.83 | CYP11B1 (0.53) | CYP11B1CYP11B2ALOX5CHRNB2CHRNA4 | |
| SCHEMBL6450540 | 0.82 | CHRNB2 (0.53) | CYP11B1CYP11B2ALOX5CHRNB2CHRNA4 | |
| SCHEMBL6294040 | 0.81 | ALDH1A1 (0.54) | CYP11B1CYP11B2ALOX5CHRNB2CHRNA4 | |
| SCHEMBL3017118 | 0.80 | CHRNB2 (0.51) | CYP11B1CYP11B2ALOX5CHRNB2CHRNA4 | |
| SCHEMBL4658201 | 0.80 | CYP11B1 (0.50) | CYP11B1CYP11B2ALOX5CHRNB2CHRNA4 | |
| SCHEMBL3017116 | 0.80 | CHRNB2 (0.51) | CYP11B1CYP11B2ALOX5CHRNB2CHRNA4 | |
| SCHEMBL3013280 | 0.80 | CHRNB2 (0.59) | CYP11B1CYP11B2ALOX5CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | ENODIA THERAPEUTICS SAS (FR) | 2022-05-19 | — | — | US | disclosed |
| EP-1556352-A1 | COMPOUNDS CAPABLE OF ACTIVATING CHOLINERGIC RECEPTORS | Targacept, Inc. (US) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004031151-A1 | COMPOUNDS CAPABLE OF ACTIVATING CHOLINERGIC RECEPTORS | TARGACEPT, INC. (US) | 2004-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | SEC61B, SEC61A1, SEC61G | CYP11B1 2802/4885CYP11B2 3479/4885ALOX5 3874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.