Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.50 |
| ▸ | TERT | O14746 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29543329 | 1.00 | APP (0.50) | APPTERTCYP2A6ALDH1A1KDM4E | |
| SCHEMBL31457375 | 0.93 | APP (0.48) | APPTERTCYP2A6ALDH1A1KDM4E | |
| SCHEMBL12566471 | 0.85 | TERT (0.64) | APPTERTALDH1A1KDM4EMEN1 | |
| SCHEMBL10000460 | 0.79 | LMNA (0.45) | APPTERTCYP2A6ALDH1A1KDM4E | |
| SCHEMBL29353067 | 0.77 | CYP2A6 (0.77) | CYP2A6ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL192166 | 0.77 | CYP2A6 (0.77) | CYP2A6ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL5593736 | 0.77 | TERT (0.55) | TERTCYP2A6ALDH1A1KDM4EMEN1 | |
| SCHEMBL372242 | 0.76 | TERT (0.54) | APPTERTCYP2A6ALDH1A1TSHR | |
| SCHEMBL29529426 | 0.76 | TERT (0.54) | APPTERTCYP2A6ALDH1A1TSHR | |
| SCHEMBL29463702 | 0.76 | TERT (0.54) | APPTERTCYP2A6ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230144841-A1 | INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN | Praxis Biotech LLC (US) | 2023-05-11 | — | — | US | disclosed |
| US-20230144841-A1 | INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN | Praxis Biotech LLC (US) | 2023-05-11 | — | — | US | disclosed |
| US-20230144841-A1 | INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN | Praxis Biotech LLC (US) | 2023-05-11 | — | — | US | disclosed |
| US-11504364-B2 | Inhibitors of fibroblast activation protein | Praxis Biotech LLC (US) | 2022-11-22 | — | — | US | disclosed |
| US-11279677-B2 | Photochromic hydrazone switches | THE TRUSTEES OF DARTMOUTH COLLEGE (US) | 2022-03-22 | — | — | US | disclosed |
| EP-3898654-A2 | INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN | Praxis Biotech LLC (US) | 2021-10-27 | — | — | EP | disclosed |
| US-20200206216-A1 | INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN | Praxis Biotech LLC | 2020-07-02 | — | — | US | disclosed |
| CN-110343065-B | Specific two-photon fluorescent probe of monoamine oxidase A as well as preparation method and application thereof | 南京工业大学 | 2020-06-30 | — | — | CN | disclosed |
| WO-2020132661-A2 | INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN | Praxis Biotech LLC (US) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020132661-A2 | INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN | Praxis Biotech LLC (US) | 2020-06-25 | — | — | WO | disclosed |
| US-20080293766-A1 | SMALL-MOLECULE INHIBITORS OF THE ANDROGEN RECEPTOR | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-11-27 | — | — | US | disclosed |
| US-20080293766-A1 | SMALL-MOLECULE INHIBITORS OF THE ANDROGEN RECEPTOR | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-11-27 | — | — | US | disclosed |
| US-20080293766-A1 | SMALL-MOLECULE INHIBITORS OF THE ANDROGEN RECEPTOR | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-11-27 | — | — | US | disclosed |
| WO-2008128100-A1 | SMALL-MOLECULE INHIBITORS OF THE ANDROGEN RECEPTOR | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-10-23 | — | — | WO | disclosed |
| WO-2008128100-A1 | SMALL-MOLECULE INHIBITORS OF THE ANDROGEN RECEPTOR | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-10-23 | — | — | WO | disclosed |
| WO-2008124812-A1 | PHEN-NAPHTHALENE AND PHEN-QUINOLINE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2008-10-16 | — | — | WO | disclosed |
| WO-2007022263-A1 | FLUOROGENIC PROBES FOR MEDIUM CHAIN ACYL-COA DEHYDROGENASE ( MCAD ) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2007-02-22 | — | — | WO | disclosed |
| US-6867320-B2 | Substituted phenylalkanoic acid derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2005-03-15 | — | — | US | disclosed |
| EP-1477472-A1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2004-11-17 | — | — | EP | disclosed |
| US-20040044258-A1 | Substituted phenylalkanoic acid derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230144841-A1 | INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN | FAP, FIBP, FRS2 | APP 2006/4885TERT 548/4885CYP2A6 4460/4885 |
| US-11504364-B2 | Inhibitors of fibroblast activation protein | FAP, FIBP, FRS2 | APP 2006/4885TERT 548/4885CYP2A6 4460/4885 |
| US-20040044258-A1 | Substituted phenylalkanoic acid derivatives and use thereof | PTGER1, CYSLTR1, PTGS1 | APP 2393/4885TERT 2382/4885CYP2A6 318/4885 |
| US-20080293766-A1 | SMALL-MOLECULE INHIBITORS OF THE ANDROGEN RECEPTOR | AR, GNRHR, FSHR | APP 2583/4885TERT 2621/4885CYP2A6 28/4885 |
| US-11279677-B2 | Photochromic hydrazone switches | CRYZ, PIN1, PPOX | APP 3427/4885TERT 709/4885CYP2A6 2633/4885 |
| US-20200206216-A1 | INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN | FAP, FIBP, FRS2 | APP 2006/4885TERT 548/4885CYP2A6 4460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.