Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 7/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.48 |
| ▸ | TAS2R14 | Q9NYV8 | 6/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.45 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.45 |
| ▸ | BMP1 | P13497 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6467324 | 0.91 | KEAP1 (0.52) | KEAP1NFE2L2TAS2R14MMP1MMP7 | |
| SCHEMBL6470238 | 0.85 | ALDH1A1 (0.45) | KEAP1NFE2L2TAS2R14 | |
| SCHEMBL6465700 | 0.74 | KEAP1 (0.50) | KEAP1NFE2L2TAS2R14MMP1MMP8 | |
| SCHEMBL6470502 | 0.74 | OPRK1 (0.42) | KEAP1NFE2L2MMP1MMP7MMP8 | |
| SCHEMBL5931099 | 0.73 | ALDH1A1 (0.51) | KEAP1NFE2L2TAS2R14F2PRSS1 | |
| SCHEMBL493487 | 0.72 | KEAP1 (0.52) | KEAP1NFE2L2TAS2R14MEP1B | |
| SCHEMBL6465065 | 0.71 | TP53 (0.54) | KEAP1NFE2L2F2 | |
| SCHEMBL28528003 | 0.70 | F2 (0.56) | MMP1MMP8MMP13F2PRSS1 | |
| SCHEMBL8620628 | 0.69 | TP53 (0.55) | KEAP1NFE2L2TAS2R14F2 | |
| SCHEMBL17230532 | 0.69 | BMP1 (0.55) | KEAP1TAS2R14MMP1MMP7MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050255998-A1 | Mixture of colour developers | CIBA SPECIALTY CHEMICALS CORP. | 2005-11-17 | — | — | US | disclosed |
| US-20050106491-A1 | Heat sensitive recording material | CIBA SPECIALTY CHEMICALS CORP. | 2005-05-19 | — | — | US | disclosed |
| EP-1480836-A1 | MIXTURE OF COLOUR DEVELOPERS | Ciba SC Holding AG (CH) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003074284-A1 | MIXTURE OF COLOUR DEVELOPERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-09-12 | — | — | WO | disclosed |
| EP-0792755-B1 | Thermosensitive recording material | OJI PAPER CO (JP) | 1998-11-11 | — | — | EP | disclosed |
| EP-0792755-A1 | Thermosensitive recording material | OJI PAPER COMPANY LIMITED (JP) | 1997-09-03 | — | — | EP | disclosed |
| US-5612280-A | AROMATIC SULFONYLUREA AND SULFONYLTHIOUREA DERIVATIVES AS COLOR DEVELOPERS; COLORFASTNESS, STORAGE STABILITY, WHITENESS | NEW OJI PAPER CO., LTD. (JP) | 1997-03-18 | — | — | US | disclosed |
| EP-0604832-A2 | Thermosensitive recording material | NEW OJI PAPER CO., LTD. (JP) | 1994-07-06 | — | — | EP | disclosed |