Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6427820 | 0.86 | KMT2A (0.47) | ALDH1A1MAPK1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL6426743 | 0.85 | CMA1 (0.57) | CMA1CHRM5ALDH1A1MAPK1MAPT | |
| SCHEMBL6428548 | 0.84 | NR1H2 (0.56) | CMA1ALDH1A1MAPK1MAPTMEN1 | |
| SCHEMBL6427122 | 0.82 | NR1H2 (0.47) | CHRM5ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6426703 | 0.79 | NR1H2 (0.41) | CHRM5ALDH1A1MAPTNR1H2NR1H3 | |
| SCHEMBL6426786 | 0.78 | MAPT (0.46) | CHRM5ALDH1A1MAPK1MAPTHPGD | |
| SCHEMBL6430888 | 0.74 | PKM (0.52) | CMA1CHRM5ALDH1A1MAPK1MAPT | |
| SCHEMBL6427708 | 0.73 | NR1H2 (0.50) | ALDH1A1MAPTKDM4EMEN1HPGD | |
| SCHEMBL6429024 | 0.71 | PTGS2 (0.46) | NR1H2NR1H3 | |
| SCHEMBL6429547 | 0.71 | CMA1 (0.54) | CMA1CHRM5ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005024755-A2 | MEDICAMENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS OR DIABETES | DECIPHERA PHARMACEUTICALS, LLC. (US) | 2005-03-17 | — | — | WO | disclosed |