Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | SDHB | P21912 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6428548 | 0.83 | NR1H2 (0.56) | NR1H2NR1H3 | |
| SCHEMBL6427166 | 0.81 | CASP1 (0.47) | NR1H2NR1H3 | |
| SCHEMBL6426783 | 0.80 | NR1H2 (0.47) | NR1H2NR1H3 | |
| SCHEMBL6427122 | 0.76 | NR1H2 (0.47) | NR1H2NR1H3 | |
| SCHEMBL6429398 | 0.74 | NPSR1 (0.41) | NR1H2NR1H3 | |
| SCHEMBL6427487 | 0.74 | DHPS (0.46) | NR1H2NR1H3 | |
| SCHEMBL6426786 | 0.72 | MAPT (0.46) | NR1H2NR1H3 | |
| SCHEMBL6525603 | 0.72 | NR1H2 (0.41) | NR1H2NR1H3 | |
| SCHEMBL6463014 | 0.71 | CMA1 (0.51) | NR1H2NR1H3 | |
| SCHEMBL6429546 | 0.71 | OPRK1 (0.40) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005024755-A2 | MEDICAMENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS OR DIABETES | DECIPHERA PHARMACEUTICALS, LLC. (US) | 2005-03-17 | — | — | WO | disclosed |