Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.32 |
| ▸ | PDE4A | P27815 | 5/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6267115 | 0.87 | ADORA2B (0.48) | PNPADORA2BADORA3ADORA2APDE4A | |
| SCHEMBL9960806 | 0.84 | PNP (0.38) | PNPADORA2BADORA3ADORA2APDE4A | |
| SCHEMBL874734 | 0.82 | ADORA2A (0.45) | PNPADORA2BADORA3ADORA2APDE4A | |
| SCHEMBL669004 | 0.79 | ADORA2B (0.50) | PNPADORA2BADORA3ADORA2APDE4A | |
| SCHEMBL3671337 | 0.79 | PNP (0.37) | PNPADORA2BADORA3ADORA2APDE4A | |
| SCHEMBL667794 | 0.79 | PDE4A (0.49) | ADORA2BADORA3ADORA2APDE4APDE4B | |
| SCHEMBL5048171 | 0.78 | PNP (0.39) | PNPADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL5503490 | 0.78 | ADORA2A (0.49) | PNPADORA2BADORA3ADORA2APDE4A | |
| SCHEMBL17186375 | 0.78 | KDM5B (0.39) | PNP | |
| SCHEMBL21748352 | 0.78 | ADORA2A (0.40) | PNPADORA2BADORA2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11839661-B2 | Rapid formation of supramolecular hydrogels by short peptide and bioactive small molecules | BRANDEIS UNIVERSITY (US) | 2023-12-12 | — | — | US | disclosed |
| US-20210128745-A1 | RAPID FORMATION OF SUPRAMOLECULAR HYDROGELS BY SHORT PEPTIDE AND BIOACTIVE SMALL MOLECULES | BRANDEIS UNIVERSITY | 2021-05-06 | — | — | US | disclosed |
| WO-2019035928-A1 | RAPID FORMATION OF SUPRAMOLECULAR HYDROGELS BY SHORT PEPTIDE AND BIOACTIVE SMALL MOLECULES | BRANDEIS UNIVERSITY (US) | 2019-02-21 | — | — | WO | disclosed |
| US-8188011-B1 | Optimization of ligand affinity for RNA targets using mass spectrometry | ISIS PHARMACEUTICALS, INC. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20050142581-A1 | Microrna as ligands and target molecules | ISIS PHARMACEUTICALS, INC. | 2005-06-30 | — | — | US | disclosed |
| US-6849660-B1 | Antimicrobial biaryl compounds | ISIS PHARMACEUTICALS, INC. (US) | 2005-02-01 | — | — | US | disclosed |
| US-6770486-B1 | IDENTIFICATION OF LIGAND COMPOUNDS THAT BIND TO TARGET MOLECULES SUCH AS PROTEINS OR STRUCTURED RNA WITH AS LITTLE AS MILLIMOLAR (MM) AFFINITY USING MASS SPECTROMETRY | ISIS PHARMACEUTICALS, INC. | 2004-08-03 | — | — | US | disclosed |