Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.57 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GNPAT | O15228 | 1/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26222742 | 1.00 | NOD1 (0.57) | NOD1SIRT6SIRT1MAPTSMN1; SMN2 | |
| SCHEMBL4609045 | 0.98 | NOD1 (0.60) | NOD1SIRT6SIRT1MAPTSMN1; SMN2 | |
| SCHEMBL10600983 | 0.98 | NOD1 (0.60) | NOD1SIRT6SIRT1MAPTSMN1; SMN2 | |
| SCHEMBL10602700 | 0.98 | NOD1 (0.60) | NOD1SIRT6SIRT1MAPTSMN1; SMN2 | |
| SCHEMBL10599977 | 0.98 | NOD1 (0.60) | NOD1SIRT6SIRT1MAPTSMN1; SMN2 | |
| SCHEMBL10603414 | 0.98 | NOD1 (0.60) | NOD1SIRT6SIRT1MAPTSMN1; SMN2 | |
| SCHEMBL10599643 | 0.98 | NOD1 (0.60) | NOD1SIRT6SIRT1MAPTSMN1; SMN2 | |
| SCHEMBL10603409 | 0.98 | NOD1 (0.60) | NOD1SIRT6SIRT1MAPTSMN1; SMN2 | |
| SCHEMBL21801849 | 0.98 | NOD1 (0.60) | NOD1SIRT6SIRT1MAPTSMN1; SMN2 | |
| SCHEMBL5982247 | 0.98 | NOD1 (0.60) | NOD1SIRT6SIRT1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | disclosed |
| US-20160213742-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF FUNGAL INFECTIONS | CIDARA THERAPEUTICS, INC. (US) | 2016-07-28 | — | — | US | disclosed |
| US-20150147309-A1 | ALLOSTERIC CHAPERONES AND USES THEREOF | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 2015-05-28 | — | — | US | disclosed |
| US-20130184462-A1 | METHOD FOR PREDICTING AND MODELING ANTI-PSYCHOTIC ACTIVITY USING VIRTUAL SCREENING MODEL | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-07-18 | — | — | US | disclosed |
| US-6903233-B2 | Process for producing optically active 3-halogenocarboxylic acid ester and 3-azidocarboxylic acid ester | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2005-06-07 | — | — | US | disclosed |
| US-20030225301-A1 | Process for producing optically active 3-halogenocarboxylic acid ester and 3-azidocarboxylic acid ester | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2003-12-04 | — | — | US | disclosed |
| EP-1344763-A1 | Process for producing optically active 3-halogenocarboxylic acid esters and 3-azide-carboxylic acid esters | Takasago International Corporation (JP) | 2003-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225301-A1 | Process for producing optically active 3-halogenocarboxylic acid ester and 3-azidocarboxylic acid ester | HDHD5, APEH, AOC3 | NOD1 1480/4885SIRT6 3951/4885SIRT1 4741/4885 |
| US-20160213742-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF FUNGAL INFECTIONS | FPR1, FPR3, FPR2 | NOD1 29/4885SIRT6 4495/4885SIRT1 3816/4885 |
| US-20150147309-A1 | ALLOSTERIC CHAPERONES AND USES THEREOF | GAA, GBA3, GBA1 | NOD1 2608/4885SIRT6 2484/4885SIRT1 3020/4885 |
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | BCAT1, BCAT2, PELP1 | NOD1 3523/4885SIRT6 2495/4885SIRT1 3931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.