Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | HSF1 | Q00613 | 5/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6465121 | 0.82 | CTSS (0.45) | — | |
| SCHEMBL6465186 | 0.81 | ALDH1A1 (0.44) | XDHHSF1FAAHCES1ALDH1A1 | |
| SCHEMBL7045889 | 0.78 | NPC1 (0.34) | XDHARHSF1FAAHCES1 | |
| SCHEMBL14110445 | 0.78 | FAAH (0.47) | XDHHSF1FAAHCES1ALDH1A1 | |
| SCHEMBL6464421 | 0.77 | ALDH1A1 (0.44) | XDHFAAHCES1ALDH1A1GAA | |
| SCHEMBL6464404 | 0.77 | DAGLA (0.48) | XDHFAAHCES1ALDH1A1 | |
| SCHEMBL6462825 | 0.76 | XDH (0.38) | XDHHSF1FAAHCES1ALDH1A1 | |
| SCHEMBL7045892 | 0.76 | CTSS (0.41) | — | |
| SCHEMBL6466172 | 0.73 | FAAH (0.36) | XDHHSF1FAAHCES1ALDH1A1 | |
| SCHEMBL14110504 | 0.71 | FAAH (0.51) | XDHHSF1FAAHCES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |