Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | XDH | P47989 | 4/20 | 0.42 |
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.41 |
| ▸ | HSF1 | Q00613 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6464421 | 0.92 | ALDH1A1 (0.44) | ALDH1A1XDHFAAHCES1DAGLA | |
| SCHEMBL6464404 | 0.91 | DAGLA (0.48) | ALDH1A1XDHFAAHCES1DAGLA | |
| SCHEMBL6462825 | 0.87 | XDH (0.38) | ALDH1A1XDHFAAHCES1HSF1 | |
| SCHEMBL14110504 | 0.84 | FAAH (0.51) | ALDH1A1XDHFAAHCES1DAGLA | |
| SCHEMBL6466172 | 0.82 | FAAH (0.36) | ALDH1A1XDHFAAHCES1HSF1 | |
| SCHEMBL6465108 | 0.81 | XDH (0.39) | ALDH1A1XDHFAAHCES1HSF1 | |
| SCHEMBL6468438 | 0.79 | FAAH (0.40) | ALDH1A1XDHFAAHCES1DAGLA | |
| SCHEMBL6468436 | 0.78 | CTSS (0.44) | ALDH1A1XDH | |
| SCHEMBL6462866 | 0.77 | FAAH (0.38) | ALDH1A1XDHFAAHCES1DAGLA | |
| SCHEMBL14110445 | 0.77 | FAAH (0.47) | ALDH1A1XDHFAAHCES1DAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |