SCHEMBL646582

SCHEMBL646582

N#Cc1ccc(C(=O)Cl)c(F)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.49
MEN1 O00255 3/20 0.49
ALDH1A1 P00352 3/20 0.47
ALOX15 P16050 1/20 0.47
MAPT P10636 3/20 0.45
PKM P14618 1/20 0.45
GAA P10253 1/20 0.45
GPR27 Q9NS67 1/20 0.44
MAP2K1 Q02750 1/20 0.43
S1PR3 Q99500 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
TRPA1 O75762 1/20 0.41
S1PR4 O95977 1/20 0.41
S1PR1 P21453 1/20 0.41
THRB P10828 1/20 0.41
LMNA P02545 1/20 0.41
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40
P4HB P07237 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL282483 0.85 ALDH1A1 (0.47) KMT2AMEN1ALDH1A1ALOX15MAPT
SCHEMBL389029 0.83 MAP2K1 (0.55) KMT2AMEN1ALDH1A1MAPTPKM
SCHEMBL29286624 0.83 MEN1 (0.50) KMT2AMEN1ALDH1A1MAPTPKM
SCHEMBL9081292 0.81 ALDH1A1 (0.47) KMT2AMEN1ALDH1A1ALOX15MAP2K1
SCHEMBL20560653 0.81 MEN1 (0.43) KMT2AMEN1ALDH1A1MAPTPKM
SCHEMBL3176877 0.81 DGAT1 (0.55) KMT2AMEN1ALDH1A1MAPTPKM
SCHEMBL10244858 0.81 KMT2A (0.52) KMT2AMEN1ALDH1A1MAPTPKM
SCHEMBL14850885 0.81 KMT2A (0.56) KMT2AMEN1ALDH1A1MAPTPKM
SCHEMBL29149950 0.81 KMT2A (0.46) KMT2AMEN1ALDH1A1MAPTPKM
SCHEMBL536199 0.80 MEN1 (0.46) KMT2AMEN1ALDH1A1MAPTPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400784-A1 Method for Screening Solvent for Extracting Polyvinyl Chloride, Method for Recycling Waste, Recycled Polyvinyl Chloride, and Composition LG CHEM, LTD. (KR) 2024-12-05 US claimed
US-20240392094-A1 Method for Screening Solvent for Polyvinyl Chloride Extraction, Recycling Method for Waste Material, and Recycled Polyvinyl Chloride and Composition LG CHEM, LTD. (KR) 2024-11-28 US claimed
CN-117897439-A Method for screening solvent for extraction of polyvinyl chloride, method for recovering waste material, and recovered polyvinyl chloride and composition 株式会社LG化学 2024-04-16 CN claimed
CN-117897440-A Method for screening solvent for extraction of polyvinyl chloride, method for recycling waste material, recycled polyvinyl chloride and composition 株式会社LG化学 2024-04-16 CN claimed
WO-2023033601-A1 METHOD FOR SCREENING SOLVENT FOR POLYVINYL CHLORIDE EXTRACTION, RECYCLING METHOD FOR WASTE MATERIAL, AND RECYCLED POLYVINYL CHLORIDE AND COMPOSITION 주식회사 엘지화학 2023-03-09 WO claimed
WO-2023033605-A1 METHOD FOR SCREENING SOLVENT FOR EXTRACTING POLYVINYL CHLORIDE, METHOD FOR RECYCLING WASTE, RECYCLED POLYVINYL CHLORIDE, AND COMPOSITION 주식회사 엘지화학 2023-03-09 WO claimed
US-12497382-B2 GLP-1R modulating compounds GILEAD SCIENCES, INC. (US) 2025-12-16 US disclosed
CN-120192278-A Azole bisamide-containing compound and preparation method and application thereof 江西天宇化工有限公司 2025-06-24 CN disclosed
CN-119874674-A GLP-1R modulating compounds 吉利德科学公司 2025-04-25 CN disclosed
CN-114630823-B GLP-1R Modulating Compounds 吉利德科学公司 2025-01-28 CN disclosed
US-20240400784-A1 Method for Screening Solvent for Extracting Polyvinyl Chloride, Method for Recycling Waste, Recycled Polyvinyl Chloride, and Composition LG CHEM, LTD. (KR) 2024-12-05 US disclosed
US-20240392094-A1 Method for Screening Solvent for Polyvinyl Chloride Extraction, Recycling Method for Waste Material, and Recycled Polyvinyl Chloride and Composition LG CHEM, LTD. (KR) 2024-11-28 US disclosed
WO-2024089170-A1 ANTIBACTERIAL COMPOUNDS Janssen Sciences Ireland Unlimited Company (IE) 2024-05-02 WO disclosed
WO-2002026720-A2 PIPERAZINE BASED INHIBITORS OF FACTOR Xa MILLENNIUM PHARMACEUTICALS, INC. (US) 2002-04-04 WO disclosed
US-20020013325-A1 Spiro compounds as inhibitors of fibrinogen-dependent platelet aggregation FISHER MATTHEW J (US) 2002-01-31 US disclosed
WO-2001094334-A1 METHODS FOR RESOLVING CHIRAL (2S) AND (2R) CHROMANES ELI LILLY & COMPANY (US) 2001-12-13 WO disclosed
US-6291469-B1 Spiro compounds as inhibitors of fibrinogen-dependent platelet aggregation ELI LILLY AND COMPANY 2001-09-18 US disclosed
EP-0854869-A1 SPIRO COMPOUNDS AS INHIBITORS OF FIBRINOGEN-DEPENDENT PLATELET AGGREGATION ELI LILLY AND COMPANY (US) 1998-07-29 EP disclosed
WO-1997011940-A1 SPIRO COMPOUNDS AS INHIBITORS OF FIBRINOGEN-DEPENDENT PLATELET AGGREGATION ELI LILLY AND COMPANY (US) 1997-04-03 WO disclosed
WO-1996001255-A1 3-(CYANOPHENYL)-PYRAZOLE DERIVATIVES AS HERBICIDES ZENECA LIMITED (GB) 1996-01-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12497382-B2 GLP-1R modulating compounds GLP1R, GIPR, GPR119 KMT2A 3870/4885MEN1 1966/4885ALDH1A1 3556/4885
US-20020013325-A1 Spiro compounds as inhibitors of fibrinogen-dependent platelet aggregation PF4, PFKP, SELP KMT2A 4697/4885MEN1 3967/4885ALDH1A1 248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.