Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7047979 | 0.89 | TBXA2R (0.41) | DAGLATBXA2RSMN1; SMN2CCR6PAX8 | |
| SCHEMBL7044843 | 0.89 | L3MBTL1 (0.39) | DAGLATBXA2RNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7186571 | 0.88 | MASP2 (0.38) | DAGLAKMT2AMEN1TBXA2RRAB9A | |
| SCHEMBL7047180 | 0.87 | P2RX7 (0.37) | DAGLA | |
| SCHEMBL7049295 | 0.83 | DAGLA (0.41) | DAGLAKMT2A | |
| SCHEMBL6467199 | 0.82 | DAGLA (0.41) | DAGLAGAATBXA2RNPC1RAB9A | |
| SCHEMBL7567535 | 0.81 | DAGLA (0.43) | DAGLAKMT2AFAAHLMNAPKM | |
| SCHEMBL7047182 | 0.81 | DAGLA (0.39) | DAGLAUSP2SMN1; SMN2MAPK1 | |
| SCHEMBL7183270 | 0.81 | MGLL (0.40) | KMT2AMEN1SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL7046959 | 0.78 | DAGLA (0.45) | DAGLAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161422-A1 | AMINE DERIVATIVES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055144-A1 | AMINE DERIVATIVES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |