Sugi Predict

Sugi Predict / Compounds / SCHEMBL64694

SCHEMBL64694

SCHEMBL64694

CCOC(=O)/C=C/c1ccco1

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 8/20 0.68
▸ ALDH1A1 P00352 5/20 0.68
▸ POLB P06746 10/20 0.65
▸ MAPT P10636 3/20 0.63
▸ CACNA1B Q00975 2/20 0.63
▸ APBA1 Q02410 2/20 0.63
▸ TDP1 Q9NUW8 12/20 0.61
▸ CTDSP1 Q9GZU7 4/20 0.61
▸ MEN1 O00255 1/20 0.61
▸ BLM P54132 1/20 0.61
▸ KMT2A Q03164 1/20 0.61
▸ APEX1 P27695 2/20 0.59
▸ APOBEC3A P31941 2/20 0.58
▸ APOBEC3G Q9HC16 2/20 0.58
▸ RECQL P46063 2/20 0.58
▸ GAA P10253 1/20 0.57
▸ PKM P14618 1/20 0.57
▸ HCAR2 Q8TDS4 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1641559 1.00 L3MBTL1 (0.68) L3MBTL1ALDH1A1POLBMAPTCACNA1B
SCHEMBL873279 0.88 POLB (0.66) L3MBTL1ALDH1A1POLBMAPTCACNA1B
SCHEMBL873278 0.88 POLB (0.66) L3MBTL1ALDH1A1POLBMAPTCACNA1B
SCHEMBL3506542 0.88 POLB (0.66) L3MBTL1ALDH1A1POLBMAPTCACNA1B
SCHEMBL7141927 0.87 L3MBTL1 (0.67) L3MBTL1ALDH1A1POLBMAPTCACNA1B
SCHEMBL7141925 0.87 L3MBTL1 (0.67) L3MBTL1ALDH1A1POLBMAPTCACNA1B
SCHEMBL7142739 0.87 ALDH1A1 (0.67) L3MBTL1ALDH1A1POLBMAPTCACNA1B
SCHEMBL7142741 0.87 ALDH1A1 (0.67) L3MBTL1ALDH1A1POLBMAPTCACNA1B
SCHEMBL2790159 0.85 POLB (0.63) L3MBTL1ALDH1A1POLBMAPTCACNA1B
SCHEMBL2790157 0.85 POLB (0.63) L3MBTL1ALDH1A1POLBMAPTCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024087650-A1 PREPARATION METHOD FOR γ-HEPTALACTONE 安徽华业香料股份有限公司 2024-05-02 — — WO claimed
JP-2003500486-A — — 2003-01-07 — — JP claimed
EP-1185524-A2 3-HETEROARYLALKYL SUBSTITUTED GABA ANALOGS WARNER-LAMBERT COMPANY (US) 2002-03-13 — — EP claimed
WO-2000073296-A2 3-HETEROARYLALKYL SUBSTITUTED GABA ANALOGS WARNER-LAMBERT COMPANY (US) 2000-12-07 — — WO claimed
US-12325702-B2 ATF6 inhibitors and uses thereof ALTOS LABS, INC. (US) 2025-06-10 — — US disclosed
WO-2024087650-A1 PREPARATION METHOD FOR γ-HEPTALACTONE 安徽华业香料股份有限公司 2024-05-02 — — WO disclosed
US-20240124434-A1 ATF6 INHIBITORS AND USES THEREOF ALTOS LABS, INC. 2024-04-18 — — US disclosed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 — — US disclosed
US-11758933-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2023-09-19 — — US disclosed
WO-2023042894-A1 FURANACRYLIC ACID ESTER POLYMER, PRODUCTION METHOD THEREFOR, AND POLYMERIZABLE MONOMER FOR USE IN PRODUCING SAID POLYMER AND PRODUCTION METHOD THEREFOR 国立研究開発法人産業技術総合研究所 2023-03-23 — — WO disclosed
CN-115466234-A Novel preparation method of gamma-heptalactone 安徽华业香料股份有限公司 2022-12-13 — — CN disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 — — EP disclosed
US-6710190-B1 ANTIEPILEPTIC, ANTIDEPRESSANT, ANXIOLYTIC, ANTIARTHRITIC, ANTIINFLAMMATORY AND ANALGESIC AGENTS; NEURODEGENERATIVE AND GASTROINTESTINAL DISORDERS; IRRITABLE BOWEL SYNDROME WARNER-LAMBERT COMPANY 2004-03-23 — — US disclosed
US-20030171625-A1 Process for producing aromatic compounds DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-09-11 — — US disclosed
EP-1342711-A2 Process for producing aromatic compounds Daicel Chemical Industries, Ltd. (JP) 2003-09-10 — — EP disclosed
EP-1185524-A2 3-HETEROARYLALKYL SUBSTITUTED GABA ANALOGS WARNER-LAMBERT COMPANY (US) 2002-03-13 — — EP disclosed
WO-2000073296-A2 3-HETEROARYLALKYL SUBSTITUTED GABA ANALOGS WARNER-LAMBERT COMPANY (US) 2000-12-07 — — WO disclosed
EP-0039989-B1 PYRIMIDONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1984-08-29 — — EP disclosed
US-4388317-A ANTIHISTAMINES SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1983-06-14 — — US disclosed
EP-0039989-A1 Pyrimidone derivatives, processes for their preparation and pharmaceutical compositions containing them SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1981-11-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240124434-A1 ATF6 INHIBITORS AND USES THEREOF ATF4, XBP1, ATF1 L3MBTL1 819/4885ALDH1A1 4447/4885POLB 2451/4885
US-12325702-B2 ATF6 inhibitors and uses thereof ATF4, XBP1, ATF1 L3MBTL1 819/4885ALDH1A1 4447/4885POLB 2451/4885
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 L3MBTL1 4816/4885ALDH1A1 978/4885POLB 4295/4885
US-20030171625-A1 Process for producing aromatic compounds PAH, HPD, HAO2 L3MBTL1 3603/4885ALDH1A1 1406/4885POLB 149/4885
US-11758933-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 L3MBTL1 4816/4885ALDH1A1 978/4885POLB 4295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.