Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440276 | 0.83 | POLB (0.49) | POLBNPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL6920262 | 0.83 | AGTR1 (0.39) | POLBNPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL6471642 | 0.77 | POLB (0.44) | POLBNPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL6918965 | 0.76 | CYP19A1 (0.46) | POLBNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL6922115 | 0.75 | ELANE (0.44) | AGTR1LMNAP2RX4NPSR1TSHR | |
| SCHEMBL7128402 | 0.75 | PTGS2 (0.47) | RAB9AALDH1A1KDM4EHPGDAGTR1 | |
| SCHEMBL6920229 | 0.75 | P2RX4 (0.47) | ALDH1A1HPGDAGTR1LMNAMAPT | |
| SCHEMBL3565673 | 0.74 | ALDH1A1 (0.45) | POLBALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL3628018 | 0.72 | POLB (0.59) | POLBNPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL28043494 | 0.68 | POLB (0.53) | POLBNPC1RAB9AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567492-A2 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | Suven Life Sciences Limited (IN) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048328-A2 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |