Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6919741 | 0.85 | AGTR1 (0.55) | AGTR1ALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL6471641 | 0.83 | POLB (0.45) | AGTR1ALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL6921230 | 0.78 | ALDH1A1 (0.40) | AGTR1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6922115 | 0.78 | ELANE (0.44) | AGTR1ABCB1PTGS2CYP1A2CYP2C9 | |
| SCHEMBL7128402 | 0.74 | PTGS2 (0.47) | AGTR1ALDH1A1HPGDKDM4EABCB1 | |
| SCHEMBL6920229 | 0.71 | P2RX4 (0.47) | AGTR1ALDH1A1HPGDABCB1MEN1 | |
| SCHEMBL6918965 | 0.70 | CYP19A1 (0.46) | ALDH1A1HPGDKDM4EPOLBMEN1 | |
| SCHEMBL6440276 | 0.69 | POLB (0.49) | ALDH1A1HPGDKDM4EPOLBMAPT | |
| SCHEMBL12181590 | 0.68 | P2RX4 (0.37) | AGTR1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6824409 | 0.68 | KDM4E (0.40) | ALDH1A1KDM4EABCB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |