Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440276 | 0.86 | POLB (0.49) | P2RX4LMNAMAPTHTTNPSR1 | |
| SCHEMBL6919741 | 0.85 | AGTR1 (0.55) | P2RX4ABCB1PTGS2LMNAMAPT | |
| SCHEMBL27647736 | 0.78 | P2RX4 (0.53) | P2RX4ABCB1PTGS1PTGS2LMNA | |
| SCHEMBL6920234 | 0.76 | P2RX4 (0.45) | P2RX4ABCB1PTGS1PTGS2LMNA | |
| SCHEMBL7128402 | 0.75 | PTGS2 (0.47) | ABCB1PTGS1PTGS2LMNAMAPT | |
| SCHEMBL6471641 | 0.75 | POLB (0.45) | P2RX4LMNAMAPTHTTAGTR1 | |
| SCHEMBL6817370 | 0.74 | P2RX4 (0.46) | P2RX4ABCB1PTGS1PTGS2LMNA | |
| SCHEMBL6922115 | 0.73 | ELANE (0.44) | P2RX4ABCB1PTGS2LMNAAGTR1 | |
| SCHEMBL6920262 | 0.71 | AGTR1 (0.39) | ABCB1PTGS2MAPTHTTAGTR1 | |
| SCHEMBL8508839 | 0.71 | AGTR1 (0.68) | P2RX4ABCB1PTGS1PTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |