Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105022 | 0.78 | HCAR2 (0.49) | MMP1MMP2MMP9MMP12ALOX5 | |
| SCHEMBL6205311 | 0.77 | HNF4A (0.45) | KDM4ETSHRALDH1A1MMP1MMP2 | |
| SCHEMBL391226 | 0.74 | KDM4E (0.50) | KDM4ETSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL4647626 | 0.70 | KDM5A (0.40) | KDM4ECA12CA9 | |
| SCHEMBL4966514 | 0.69 | BRS3 (0.34) | KDM4EMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL8122044 | 0.69 | MMP1 (0.51) | KDM4EAKR1B1MEN1KMT2AALDH1A1 | |
| SCHEMBL15567932 | 0.68 | ALDH1A1 (0.34) | KDM4EMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL30360660 | 0.67 | TSHR (0.59) | KDM4ETSHRAKR1B1MEN1KMT2A | |
| SCHEMBL8482161 | 0.67 | TSHR (0.59) | KDM4ETSHRAKR1B1MEN1KMT2A | |
| SCHEMBL8482166 | 0.67 | TSHR (0.59) | KDM4ETSHRAKR1B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |