Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.37 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3426193 | 0.89 | CA2 (0.46) | CA2CAMK2ACES2CES1AKR1B1 | |
| SCHEMBL2732935 | 0.83 | LMNA (0.54) | RXRARXRBCA2CAMK2ACES2 | |
| SCHEMBL6472226 | 0.82 | CES2 (0.42) | TPMTRXRARXRBCA2CAMK2A | |
| SCHEMBL83884 | 0.81 | CA2 (0.61) | CA2CAMK2ALMNACTBP2 | |
| SCHEMBL41907 | 0.80 | CES1 (0.58) | CES2CES1AKR1B1ABCC4LMNA | |
| SCHEMBL6472518 | 0.79 | CES2 (0.40) | TPMTRXRARXRBCA2CAMK2A | |
| SCHEMBL6442701 | 0.79 | ALDH1A1 (0.52) | RXRARXRBCA2CAMK2ALMNA | |
| SCHEMBL1629363 | 0.79 | CTBP2 (0.56) | LMNACTBP2 | |
| SCHEMBL1921797 | 0.79 | CTBP2 (0.56) | LMNAGAACTBP2 | |
| SCHEMBL397389 | 0.79 | MEN1 (0.49) | LMNAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005109041-A1 | COMPOSITIONS FOR USE IN THE MANUFACTURE OF LENSES | MEDICAL POLYMERS LIMITED (GB) | 2005-11-17 | — | — | WO | claimed |
| WO-2005109041-A1 | COMPOSITIONS FOR USE IN THE MANUFACTURE OF LENSES | MEDICAL POLYMERS LIMITED (GB) | 2005-11-17 | — | — | WO | disclosed |
| US-6040408-A | Radiopaque polymers and methods for preparation thereof | BIOMAT B.V. (NL) | 2000-03-21 | — | — | US | disclosed |
| EP-0777503-B1 | RADIOPAQUE POLYMERS AND METHODS FOR PREPARATION THEREOF | BIOMAT BV (NL) | 1999-11-17 | — | — | EP | disclosed |
| EP-0777503-A1 | RADIOPAQUE POLYMERS AND METHODS FOR PREPARATION THEREOF | Biomat B.V. (NL) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996005872-A1 | RADIOPAQUE POLYMERS AND METHODS FOR PREPARATION THEREOF | BIOMAT B.V. (NL) | 1996-02-29 | — | — | WO | disclosed |