Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CASP1 | P29466 | 3/20 | 0.51 |
| ▸ | CASP7 | P55210 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.51 |
| ▸ | CBFB | Q13951 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TNIK | Q9UKE5 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6473728 | 0.90 | MAPT (0.50) | MAPTKDM4EALDH1A1CASP1CASP7 | |
| SCHEMBL5202344 | 0.89 | SCN9A (0.47) | MAPTKDM4EALDH1A1CASP1CASP7 | |
| SCHEMBL6480001 | 0.87 | MAPT (0.49) | MAPTKDM4EALDH1A1CASP1CASP7 | |
| SCHEMBL6474559 | 0.81 | GAA (0.43) | MAPTKDM4EALDH1A1CASP1CASP7 | |
| SCHEMBL6474471 | 0.81 | BCL6 (0.49) | MAPTALDH1A1GAALMNATSHR | |
| SCHEMBL5204470 | 0.77 | MEN1 (0.42) | MAPTALDH1A1CASP1CASP7LMNA | |
| SCHEMBL6481407 | 0.74 | AURKA (0.47) | MAPTKDM4EALDH1A1CASP1CASP7 | |
| SCHEMBL6474359 | 0.73 | MEN1 (0.43) | MAPTALDH1A1CASP1CASP7LMNA | |
| SCHEMBL6480285 | 0.71 | AURKA (0.53) | MAPTALDH1A1CASP1CASP7LMNA | |
| SCHEMBL6472908 | 0.69 | TTBK1 (0.43) | MAPTKDM4EALDH1A1CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916820-B1 | Neurotrophic substituted pyrimidines | KRENITSKY PHARMACEUTICALS, INC. (US) | 2005-07-12 | — | — | US | claimed |