SCHEMBL4482936

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6476010	0.90	HTR6 (0.81)	HTR6CCNT1CDK9ESR1MEN1
	SCHEMBL4480862	0.90	HTR6 (1.00)	HTR6MAPTPKMCCNT1CDK9
	SCHEMBL6475723	0.89	HTR6 (0.80)	HTR6MAPTPKMCCNT1CDK9
	Water SCHEMBL4559433	0.89	HTR6 (0.98)	HTR6MAPTPKMCCNT1CDK9
	Water SCHEMBL4559431	0.89	HTR6 (0.98)	HTR6MAPTPKMCCNT1CDK9
	SCHEMBL4487505	0.83	HTR6 (0.68)	HTR6MAPTGAAHTR2CMEN1
	SCHEMBL4477508	0.83	HTR6 (0.80)	HTR6MAPTPKMCCNT1CDK9
	SCHEMBL6472087	0.81	HTR6 (0.76)	HTR6MAPTHTR2CKMT2ALMNA
	SCHEMBL3324653	0.79	HTR6 (0.72)	HTR6
	SCHEMBL6473187	0.72	MAPT (0.54)	HTR6MAPTATICPKMPNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.