Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 3/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.53 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2605637 | 0.89 | ADRB2 (0.61) | ADRB3ADRB2ADRB1KDM4EALDH1A1 | |
| SCHEMBL19196175 | 0.83 | LMNA (0.63) | ADRB3ADRB2ADRB1KDM4EALDH1A1 | |
| SCHEMBL19181215 | 0.83 | LMNA (0.63) | ADRB3ADRB2ADRB1KDM4EALDH1A1 | |
| SCHEMBL22964154 | 0.78 | CALM1 (0.64) | CALM1ALDH1A1TSHRHPGDHTT | |
| SCHEMBL14740400 | 0.78 | MAPT (0.56) | ADRB3ADRB2ADRB1ALDH1A1MAPT | |
| SCHEMBL109055 | 0.72 | ADRB3 (0.65) | ADRB3ADRB2ADRB1 | |
| SCHEMBL1912854 | 0.72 | KMT2A (0.62) | KDM4EALDH1A1TSHRHPGDMAPT | |
| SCHEMBL7116286 | 0.72 | ADRB2 (0.65) | ADRB3ADRB2ADRB1ALDH1A1HTT | |
| SCHEMBL109279 | 0.69 | ALDH1A1 (0.67) | KDM4EALDH1A1TSHRHPGDGAA | |
| SCHEMBL1039148 | 0.69 | ALDH1A1 (0.76) | KDM4EALDH1A1TSHRHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6890955-B2 | Aryloxypropanolamine derivatives, method of preparation and applications thereof | VIRBAC SA (FR) | 2005-05-10 | — | — | US | disclosed |
| US-20030158259-A1 | Aryloxypropanolamine derivatives, method of preparation and applications thereof | VIRBAC SA | 2003-08-21 | — | — | US | disclosed |
| EP-0937063-B1 | ARYLOXYPROPANOLAMINE DERIVATIVES, METHOD OF PREPARATION AND APPLICATIONS THEREOF | VIRBAC SA (FR) | 2002-04-10 | — | — | EP | disclosed |
| US-20020019440-A1 | Aryloxypropanolamine derivatives, method of preparation and applications thereof | VIRBAC SA | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019440-A1 | Aryloxypropanolamine derivatives, method of preparation and applications thereof | FABP4, CCNO, PAOX | ADRB3 38/4885ADRB2 43/4885ADRB1 151/4885 |
| US-20030158259-A1 | Aryloxypropanolamine derivatives, method of preparation and applications thereof | PAOX, ACOX3, FABP4 | ADRB3 38/4885ADRB2 40/4885ADRB1 133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.