SCHEMBL648803

SCHEMBL648803

O=S(=O)(Nc1ncc(C(O)(C(F)(F)F)C(F)(F)F)s1)c1ccc(Cl)cc1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ FFAR2 O15552 3/20 0.54
▸ MEN1 O00255 2/20 0.53
▸ KMT2A Q03164 2/20 0.53
▸ MLYCD O95822 4/20 0.48
▸ LMNA P02545 2/20 0.48
▸ SMN1; SMN2 Q16637 1/20 0.48
▸ ALOX12 P18054 1/20 0.44
▸ HTT P42858 1/20 0.44
▸ KDM1A O60341 2/20 0.44
▸ PPIA P62937 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ SCN3A Q9NY46 1/20 0.42
▸ CES1 P23141 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1897000 0.89 MLYCD (0.49) FFAR2MEN1KMT2AMLYCDLMNA
SCHEMBL7978716 0.71 STAT3 (0.59) MEN1KMT2ALMNASMN1; SMN2ALOX12
SCHEMBL3255724 0.71 LMNA (0.49) MEN1KMT2ALMNASMN1; SMN2ALOX12
SCHEMBL5960294 0.71 ALOX5 (0.46) MLYCDALDH1A1
SCHEMBL2942043 0.70 RORA (0.74) MEN1KMT2AALDH1A1CES1
SCHEMBL5391636 0.69 MEN1 (1.00) FFAR2MEN1KMT2ALMNASMN1; SMN2
SCHEMBL3099124 0.69 SCN3A (0.49) MEN1KMT2ALMNASMN1; SMN2ALOX12
SCHEMBL1897896 0.68 FFAR2 (0.45) FFAR2MLYCD
SCHEMBL6624588 0.66 KMT2A (0.64) MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL3154592 0.66 CA1 (0.55) MEN1KMT2ALMNASMN1; SMN2ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8262945-B2 Stabilization of photochromic systems BASF SE (DE) 2012-09-11 — — US claimed
EP-1411929-B1 MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS CHUGAI PHARMACEUTICAL CO LTD (JP) 2011-05-11 — — EP claimed
US-20100048773-A1 AGRICULTURAL ARTICLES BONORA MICHELA 2010-02-25 — — US claimed
US-20100048774-A1 STABILIZER MIXTURES GUGUMUS FRANCOIS 2010-02-25 — — US claimed
US-7595008-B2 Mixture containing steric hindred amine compound with zinc and magnesium salt; photostability; heat and oxidation resistance; for polymers CIBA SPECIALTY CHEMICALS CORPORATION (US) 2009-09-29 — — US claimed
EP-1440115-B1 CROSSLINKING OF UNSATURATED POLYESTERS BY THE USE OF HYDROXYLAMINE-ESTERS CIBA HOLDING INC (CH) 2009-08-05 — — EP claimed
EP-1115765-B1 GRAFTING OF ETHYLENICALLY UNSATURATED MONOMERS ONTO POLYMERS CIBA HOLDING INC (CH) 2009-06-24 — — EP claimed
US-20090111917-A1 Stabilized articles BONORA MICHELA 2009-04-30 — — US claimed
US-20090105379-A1 Stabilizer mixtures GUGUMUS FRANCOIS 2009-04-23 — — US claimed
US-20090093572-A1 Stabilizer mixtures GUGUMUS FRANCOIS 2009-04-09 — — US claimed
EP-0881222-A1 A process for the preparation of polytriazine products containing 2,2,6,6-tetramethyl-4-piperidyl groups Ciba SC Holding AG (CH) 1998-12-02 — — EP claimed
EP-0850938-A1 Triazine compounds containing 2,2,6,6-tetramenthyl-4-piperidyl groups as stabilizers for organic materials Ciba SC Holding AG (CH) 1998-07-01 — — EP claimed
EP-0782994-A1 Block oligomers containing 2,2,6,6-tetramethyl-4-piperidyl groups as stabilizers for organic materials Ciba SC Holding AG (CH) 1997-07-09 — — EP claimed
EP-0548015-B1 Tetramethylpiperidine compounds for use as stabilisers for organic materials CIBA GEIGY AG (CH) 1996-01-03 — — EP claimed
EP-0627428-A1 Piperidine-triazine compounds as light heat and oxidation stabilizers for organic materials CIBA-GEIGY AG (CH) 1994-12-07 — — EP claimed
EP-0546998-B1 Process for preparing N,N'-bis(hydrocarbyloxycarbonyl)-N,N'-bis(2,2,6,6-tetramethyl-4-piperidyl)diamines CIBA GEIGY AG (CH) 1994-11-23 — — EP claimed
EP-0548015-A1 Tetramethylpiperidine compounds for use as stabilisers for organic materials CIBA-GEIGY AG (CH) 1993-06-23 — — EP claimed
EP-0546998-A1 Process for preparing N,N'-bis(hydrocarbyloxycarbonyl)-N,N'-bis(2,2,6,6-tetramethyl-4-piperidyl)diamines CIBA-GEIGY AG (CH) 1993-06-16 — — EP claimed
EP-0523007-A1 Novel tetramethylpiperidine compounds for use as stabilisers for organic materials CIBA-GEIGY AG (CH) 1993-01-13 — — EP claimed
EP-0518807-A1 Piperidine compounds for use as stabilisers for organic materials CIBA-GEIGY AG (CH) 1992-12-16 — — EP claimed
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