Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.63 |
| ▸ | MMP8 | P22894 | 3/20 | 0.56 |
| ▸ | MMP13 | P45452 | 3/20 | 0.56 |
| ▸ | MMP12 | P39900 | 2/20 | 0.56 |
| ▸ | MMP1 | P03956 | 2/20 | 0.56 |
| ▸ | MMP7 | P09237 | 1/20 | 0.56 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491355 | 0.87 | CA2 (0.55) | IDO1MMP8MMP13MMP12MMP1 | |
| SCHEMBL6793104 | 0.83 | IDO1 (0.59) | IDO1MMP8MMP13MMP12MMP1 | |
| SCHEMBL8987446 | 0.83 | IDO1 (0.59) | IDO1MMP8MMP13MMP12MMP1 | |
| SCHEMBL16914880 | 0.83 | MMP8 (0.64) | IDO1MMP8MMP13MMP12MMP1 | |
| SCHEMBL10890460 | 0.83 | IDO1 (0.59) | IDO1MMP8MMP13MMP12MMP1 | |
| SCHEMBL15754219 | 0.81 | L3MBTL1 (0.64) | IDO1MMP8MMP13MMP12MMP1 | |
| SCHEMBL15622087 | 0.81 | IDO1 (0.68) | IDO1MMP8MMP13MMP12MMP1 | |
| SCHEMBL426660 | 0.79 | IDO1 (0.56) | IDO1MMP8MMP13MMP12MMP1 | |
| SCHEMBL426661 | 0.79 | IDO1 (0.56) | IDO1MMP8MMP13MMP12MMP1 | |
| SCHEMBL3836194 | 0.79 | MMP8 (0.58) | IDO1MMP8MMP13MMP12MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | APOB, APOL1, SCARB1 | IDO1 696/4885MMP8 1358/4885MMP13 2294/4885 |
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | IDO1 246/4885MMP8 1156/4885MMP13 1599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.