Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.34 |
| ▸ | ITGAV | P06756 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.33 |
| ▸ | PPARG | P37231 | 4/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
| ▸ | PYGM | P11217 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6500955 | 0.90 | KDM4C (0.40) | ALOX5APITGB3ITGB1ITGAVITGA2B | |
| SCHEMBL6487346 | 0.87 | ALDH1A1 (0.38) | ALOX5APPTGESALOX5LTC4SAGTR1 | |
| SCHEMBL6489174 | 0.80 | PIK3C2B (0.37) | ALOX5APPTGESALOX5LTC4SAGTR1 | |
| SCHEMBL6490213 | 0.77 | MRGPRX4 (0.40) | ALOX5APPTGESALOX5LTC4SPPARG | |
| SCHEMBL6489503 | 0.76 | CYSLTR1 (0.42) | PPARGDCTPP1 | |
| SCHEMBL6492577 | 0.75 | DCTPP1 (0.41) | ALOX5APPTGESALOX5LTC4SDCTPP1 | |
| SCHEMBL6488028 | 0.74 | AGTR1 (0.40) | AGTR1DCTPP1 | |
| SCHEMBL6486764 | 0.74 | DCTPP1 (0.44) | ALOX5APPTGESALOX5LTC4SAGTR1 | |
| SCHEMBL6503273 | 0.74 | CYP1A2 (0.42) | AGTR1PPARGMEN1KMT2A | |
| SCHEMBL6501198 | 0.73 | NR4A2 (0.48) | ALOX5APPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | ALOX5AP 4663/4885ITGB3 2674/4885ITGB1 2573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.