Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.37 |
| ▸ | F10 | P00742 | 3/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | KLK1 | P06870 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5210452 | 0.94 | OPRM1 (0.35) | F2F10ITGB3ITGA2BOPRD1 | |
| Trifluoroacetic Acid SCHEMBL5214432 | 0.89 | ACHE (0.42) | OPRD1OPRM1OPRK1CYP2C19ACHE | |
| Trifluoroacetic Acid SCHEMBL5245608 | 0.86 | OPRM1 (0.36) | F2F10OPRD1OPRM1OPRK1 | |
| Trifluoroacetic Acid SCHEMBL5215547 | 0.85 | RIPK1 (0.36) | F2F10OPRD1OPRM1OPRK1 | |
| Trifluoroacetic Acid SCHEMBL5211441 | 0.85 | RIPK1 (0.38) | F2F10OPRD1OPRM1OPRK1 | |
| Trifluoroacetic Acid SCHEMBL5210720 | 0.85 | HSD17B3 (0.38) | MAPTALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5209869 | 0.85 | OPRD1 (0.34) | F2F10OPRD1OPRM1OPRK1 | |
| Trifluoroacetic Acid SCHEMBL5629383 | 0.85 | POLB (0.36) | F2OPRD1OPRM1OPRK1TP53 | |
| Trifluoroacetic Acid SCHEMBL5211445 | 0.84 | POLB (0.44) | F2F10OPRD1OPRM1MAPT | |
| Trifluoroacetic Acid SCHEMBL5212450 | 0.84 | RIPK1 (0.39) | F2F10OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916957-B2 | Serine protease inhibitors | TULARIK LIMITED (GB) | 2005-07-12 | — | — | US | disclosed |
| US-20030018059-A1 | Serine protease inhibitors | PROTHERICS MOLECULAR DESIGN LIMITED (GB) | 2003-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018059-A1 | Serine protease inhibitors | TPSAB1, PRSS1, SERPINB1 | F2 122/4885F10 149/4885ITGB3 2185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.