SCHEMBL64927

SCHEMBL64927

COc1cccc(C(=O)Cl)c1C

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.49
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
CA14 Q9ULX7 1/20 0.47
HTT P42858 1/20 0.44
UTS2R Q9UKP6 1/20 0.44
ABCB1 P08183 1/20 0.44
KCNK3 O14649 1/20 0.44
KCNK9 Q9NPC2 1/20 0.44
TLR2 O60603 1/20 0.43
TLR1 Q15399 1/20 0.43
TLR6 Q9Y2C9 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL28590386 0.92 RAB9A (0.48) CTSDCA12CA1CA2CA7
SCHEMBL7496866 0.82 MAPT (0.46) CTSDCA12CA1CA2CA7
SCHEMBL698393 0.82 LMNA (0.53) CTSDCA12CA1CA2CA7
SCHEMBL311839 0.82 HTT (0.59) CA12CA1CA2CA7CA9
SCHEMBL29959614 0.82 HTT (0.59) CA12CA1CA2CA7CA9
SCHEMBL431 0.82 CTSD (0.63) CTSDHTTKCNK3KCNK9
SCHEMBL29392137 0.82 CTSD (0.63) CTSDHTTKCNK3KCNK9
SCHEMBL414201 0.81 ACHE (0.56) HTT
SCHEMBL2300929 0.81 ALDH1A1 (0.50)
SCHEMBL9357148 0.81 JAK2 (0.56) CTSDCA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113248351-B Preparation method of 6-chloro-2-methoxytoluene and synthetic process of methoxyfenozide 绍兴上虞新银邦生化有限公司 2022-10-11 CN claimed
CN-113105323-B Green preparation process of 2-methyl-3-methoxybenzoyl chloride 江苏永安化工有限公司 2022-07-19 CN claimed
CN-113248351-A Preparation method of 6-chloro-2-methoxytoluene and synthetic process of methoxyfenozide 绍兴上虞新银邦生化有限公司 2021-08-13 CN claimed
CN-113105323-A Green preparation process of 2-methyl-3-methoxybenzoyl chloride 江苏永安化工有限公司 2021-07-13 CN claimed
CN-110627678-A Synthesis process of methoxyfenozide 李德平 2019-12-31 CN claimed
CN-109384667-A A kind of synthesis technology of 2- methyl -3- methoxy benzoyl chloride 江苏永安化工有限公司 2019-02-26 CN claimed
CN-108828121-A A kind of white detection method of content for setting the high nojirimycin of α-in medicinal material 华润三九医药股份有限公司 2018-11-16 CN claimed
CN-107176908-A A kind of synthetic method of the methoxy benzoyl chloride of 2 methyl 3 江苏科菲特生化技术股份有限公司 2017-09-19 CN claimed
EP-0639559-B1 Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines ROHM & HAAS (US) 1997-10-15 EP claimed
EP-0639559-A1 Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines ROHM AND HAAS COMPANY (US) 1995-02-22 EP claimed
US-12441708-B2 Cereblon ligands and bifunctional compounds comprising the same ARVINAS OPERATIONS, INC. (US) 2025-10-14 US disclosed
US-20250313547-A1 CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME ARVINAS OPERATIONS INC (US) 2025-10-09 US disclosed
CN-113896712-B Diamide compound containing cyclic amino acid 华东理工大学 2024-04-09 CN disclosed
CN-110612294-B Human cerebulin ligands and bifunctional compounds comprising same 阿尔维纳斯运营股份有限公司 2024-01-16 CN disclosed
US-20230183209-A1 CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME ARVINAS OPERATIONS, INC. (US) 2023-06-15 US disclosed
US-5344958-A From 3-methoxy-2-(substituted)benzoic acid or ester ROHM AND HAAS COMPANY (US) 1994-09-06 US disclosed
EP-0602794-A2 Insecticidal N'-substituted-N, N'-diacylhydrazines ROHM AND HAAS COMPANY (US) 1994-06-22 EP disclosed
WO-1993014086-A1 SUBSTITUTED 1-ISOQUINOLONE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS SYNTEX (U.S.A.) INC. (US) 1993-07-22 WO disclosed
CN-1057452-A Dibenzoyl alkyl-alkyl cyanides ROHM & HAAS (US) 1992-01-01 CN disclosed
EP-0461809-A1 Dibenzoylalkylcyanohydrazines ROHM AND HAAS COMPANY (US) 1991-12-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230183209-A1 CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME CRBN, CBL, MDM2 CTSD 1381/4885CA12 2628/4885CA1 982/4885
US-20250313547-A1 CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME CRBN, CBL, MDM2 CTSD 1381/4885CA12 2628/4885CA1 982/4885
US-12441708-B2 Cereblon ligands and bifunctional compounds comprising the same CRBN, CBL, MDM2 CTSD 1381/4885CA12 2628/4885CA1 982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.