Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.57 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.54 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.54 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.54 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.54 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.54 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.54 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.54 |
| ▸ | EIF4E | P06730 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10058714 | 0.89 | PTPN11 (0.65) | SMN1; SMN2PTPN11PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL6491926 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2PTPN11PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL6640302 | 0.87 | PTPN11 (0.59) | SMN1; SMN2PTPN11HCRTR1HCRTR2KDM4E | |
| SCHEMBL6487707 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2PTPN11PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL3816798 | 0.84 | SMN1; SMN2 (0.82) | SMN1; SMN2PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL6501365 | 0.82 | PTPN11 (0.54) | SMN1; SMN2PTPN11PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL6489327 | 0.81 | ALDH1A1 (0.59) | SMN1; SMN2PTPN11PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL6498907 | 0.79 | ALDH1A1 (0.61) | SMN1; SMN2EIF4EKDM4ENPC1ALDH1A1 | |
| SCHEMBL15935983 | 0.79 | TAS1R3 (0.54) | SMN1; SMN2PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL6498615 | 0.78 | FOLH1 (0.54) | SMN1; SMN2PTPN11EIF4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | SMN1; SMN2 1921/4885PTPN11 1450/4885PRKAB2 3183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.