Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.54 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CTRC | Q99895 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | EIF4E | P06730 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MARS1 | P56192 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14611035 | 0.88 | SLC6A4 (0.45) | FOLH1LTB4R2SMN1; SMN2CTRCRAB9A | |
| SCHEMBL6491569 | 0.86 | FOLH1 (0.55) | FOLH1LTB4R2HSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL3737187 | 0.85 | FOLH1 (0.71) | FOLH1LTB4R2HSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL3168574 | 0.84 | METAP2 (0.54) | FOLH1LTB4R2HSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL3823506 | 0.84 | FOLH1 (0.54) | FOLH1LTB4R2HSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL6498907 | 0.83 | ALDH1A1 (0.61) | FOLH1LTB4R2HSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL11527291 | 0.81 | SMN1; SMN2 (0.49) | LTB4R2HSD17B10SMN1; SMN2RAB9APPARG | |
| SCHEMBL6487907 | 0.81 | PSEN1 (0.56) | FOLH1HSD17B10SMN1; SMN2RAB9APTPN11 | |
| SCHEMBL6499129 | 0.79 | HSD17B10 (0.51) | HSD17B10SMN1; SMN2RAB9AEIF4ENPC1 | |
| SCHEMBL6492999 | 0.78 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9APTPN11EIF4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | FOLH1 2079/4885LTB4R2 400/4885HSD17B10 901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.