Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6489918 | 0.88 | ALDH1A1 (0.43) | MAPTALDH1A1CRHBPCRHR2SIRT1 | |
| SCHEMBL6499711 | 0.85 | SIRT1 (0.42) | SIRT1RAB9ACCR2 | |
| SCHEMBL6488833 | 0.82 | SIRT1 (0.40) | MAPTALDH1A1CRHBPCRHR2SIRT1 | |
| SCHEMBL6497572 | 0.81 | GAA (0.42) | MAPTALDH1A1CRHBPCRHR2SIRT1 | |
| SCHEMBL6499921 | 0.79 | L3MBTL1 (0.46) | MAPTALDH1A1CRHBPCRHR2SIRT1 | |
| SCHEMBL6496070 | 0.77 | MAPT (0.43) | MAPTALDH1A1CRHBPCRHR2SIRT1 | |
| SCHEMBL6490802 | 0.77 | SIRT1 (0.43) | SIRT1CCR2 | |
| SCHEMBL26640360 | 0.77 | PKM (0.46) | MAPTALDH1A1POLBRAB9ACYP2C19 | |
| SCHEMBL6501746 | 0.74 | HDAC1 (0.37) | MAPTALDH1A1CRHBPCRHR2RAB9A | |
| SCHEMBL18519552 | 0.73 | CYP2C19 (0.41) | MAPTALDH1A1POLBRAB9ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | MAPT 4202/4885ALDH1A1 1603/4885CRHBP 2517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.