Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506411 | 0.89 | SMN1; SMN2 (0.44) | SMN1; SMN2TAS1R3TAS1R1L3MBTL1MAPT | |
| SCHEMBL6499488 | 0.86 | KMT2A (0.56) | ALDH1A1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL6388645 | 0.85 | L3MBTL1 (0.60) | ALDH1A1HPGDSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL6390689 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6500692 | 0.81 | RAB9A (0.52) | ALDH1A1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL6506803 | 0.81 | POLB (0.54) | ALDH1A1HPGDKMT2ANPC1RAB9A | |
| SCHEMBL6388618 | 0.81 | POLB (0.54) | ALDH1A1HPGDKMT2ANPC1RAB9A | |
| SCHEMBL6502145 | 0.79 | NPC1 (0.50) | ALDH1A1SMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL6502232 | 0.79 | KMT2A (0.50) | ALDH1A1HPGDSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL6501631 | 0.79 | POLB (0.51) | ALDH1A1HPGDNPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239853-A1 | New compounds | HSD11B1, CYP11B1, HSD3B1 | ALDH1A1 67/4885HPGD 66/4885SMN1; SMN2 3733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.