Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506411 | 0.88 | SMN1; SMN2 (0.44) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL6499268 | 0.86 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL6502145 | 0.81 | NPC1 (0.50) | KMT2AMEN1ALDH1A1CYP2C19TSHR | |
| SCHEMBL6505116 | 0.78 | S1PR2 (0.39) | KMT2AMEN1GAAALDH1A1CYP2C19 | |
| SCHEMBL6388630 | 0.78 | SMN1; SMN2 (0.41) | KMT2AMEN1POLBTDP1L3MBTL1 | |
| SCHEMBL6506236 | 0.78 | LMNA (0.43) | KMT2AMEN1GAAALDH1A1TDP1 | |
| SCHEMBL6500692 | 0.78 | RAB9A (0.52) | KMT2AMEN1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL6502232 | 0.78 | KMT2A (0.50) | KMT2AMEN1GAAALDH1A1POLB | |
| SCHEMBL6387585 | 0.78 | POLB (0.44) | KMT2APOLBTDP1L3MBTL1LMNA | |
| SCHEMBL6392636 | 0.78 | POLB (0.44) | KMT2APOLBTDP1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | claimed |
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239853-A1 | New compounds | HSD11B1, CYP11B1, HSD3B1 | KMT2A 3213/4885MEN1 979/4885GAA 522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.