Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502232 | 0.89 | KMT2A (0.50) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL6506411 | 0.86 | SMN1; SMN2 (0.44) | TAS1R3TAS1R1SMN1; SMN2TSHRNPSR1 | |
| SCHEMBL6506236 | 0.85 | LMNA (0.43) | KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL6393301 | 0.84 | RAB9A (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6390207 | 0.84 | RAB9A (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6394209 | 0.84 | RAB9A (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6426518 | 0.84 | NPC1 (0.48) | NPC1RAB9ATAS1R3TAS1R1SMN1; SMN2 | |
| SCHEMBL6505116 | 0.83 | S1PR2 (0.39) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL6509241 | 0.82 | KMT2A (0.36) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL6499488 | 0.81 | KMT2A (0.56) | KMT2AALDH1A1TSHRMEN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | claimed |
| US-20050239853-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239853-A1 | New compounds | HSD11B1, CYP11B1, HSD3B1 | NPC1 277/4885RAB9A 2649/4885TAS1R3 4345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.